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Assessment of gallbladder function using ceruletide in oral cholecystography

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Abstract

A dose of 0.3 μg/kg body weight of ceruletide was assessed for its effect on gallbladder contraction and bile duct delineation following oral cholecystography. Nausea, vomiting, and abdominal pain sometimes occurred after ceruletide. No relationship was found after ceruletide administration between the radiologic appearances of the biliary tract and reproduction of the patients' biliary-type symptoms. Ceruletide cholecystography is regarded as an inaccurate investigation of biliary tract function.

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References

  1. Carratu R, Arcangeli G, Pallone F: Effects of Caerulin on the human biliary tract.Rend Gastroenterol 3:28–33, 1971

    Google Scholar 

  2. Bertaccini G, Agosti A: Action of Caerulin on intestinal mobility in man.Gastroenterology 60:55–60, 1971

    CAS  PubMed  Google Scholar 

  3. Arnold JD, Boyer S, Shemano I: Comparative cholecystokinin effect of I.M. Ceruletide, I.V. sincalide oral fatty meal and I.M. placebo.Clin Pharmacol Ther 27:245, 1980

    Google Scholar 

  4. Davidsen D, Jørgensen J: Gallbladder emptying with Ceruletide in oral cholecystography.Acta Radiol Diagn 22:165–169, 1981

    CAS  Google Scholar 

  5. Sargent EN, Wieler M, Wallis J: Cholecystokinetic cholecystography: comparison of effect of intramuscular Ceruletide to a fatty meal.Am J Roentgenol 133:489–492, 1979

    CAS  Google Scholar 

  6. Wetzner SM, Vincent ME, Rollins AH: Ceruletide associated cholecystography — a clinical assessment.Radiology 131:23–26, 1979

    CAS  PubMed  Google Scholar 

  7. Goldberg HI: Cholecystokinin cholecystography.Semin Roentgenol 11:175–179, 1976

    CAS  PubMed  Google Scholar 

  8. Goldstein F, Grant RE, Margules M: Cholecystokinin cholecystography in differential diagnosis of acalculous gall-bladder disease.Am J Dig Dis 19:835–849, 1974

    CAS  PubMed  Google Scholar 

  9. Nathan MH, Newman A, Murray DJ, Camponova R: Cholecystokinin cholecystography.AJR 110:240–251, 1970

    CAS  Google Scholar 

  10. Cozzolino HJ, Goldstein F, Greening RR, Wirts CW: The cystic duct syndrome.JAMA 185:920–924, 1963

    CAS  PubMed  Google Scholar 

  11. Madsen PER, Andersen JF, Jensen KB, Andersen D: Cholecystokinin — cholecystography and cholecystokinesis — pain provocation test. Evaluation of patient with biliary colic without gallstones.Ugeskr Laeger 143:2963–2970, 1981

    Google Scholar 

  12. Ivy AC: Motor dysfunction of the biliary tract — an analytical and critical consideration.AJR 57:1–11, 1947

    Google Scholar 

  13. Berk RN: Cholecystography in diagnosis of chronic acalculous cholecystitis and biliary function.Gastrointest Radiol 1:325–330, 1977

    CAS  PubMed  Google Scholar 

  14. Dunn FG, Christensen EC, Reynolds J, Jones U, Fordtran JS: Cholecystokinin cholecystography.JAMA 228:997–1003, 1974

    Article  CAS  PubMed  Google Scholar 

  15. McConnell CA, Whitehouse GH, Evans AF: Gallbladder contraction and bile duct opacification in oral cholecystography.Br J Radiol 56:371–376, 1983

    CAS  PubMed  Google Scholar 

  16. Camishion RC, Goldstein F: Partial noncalculous cystic duct obstruction (cystic duct syndrome).Surg Clin North Am 47:1107–1114, 1967

    CAS  PubMed  Google Scholar 

  17. Valberg LS, Javvari M, Kerr JW, Curtis AC, Rachmand S, Prentice RSA: Biliary pain in young women in the absence of gall stones.Gastroenterology 60:1020–1026, 1971

    CAS  PubMed  Google Scholar 

  18. Nora PF, McCarthy W, Sanez N: Cholecystokinin cholecystography in acalculous gallbladder disease.Arch Surg 108:507–511, 1974

    CAS  PubMed  Google Scholar 

  19. Freeman JB, Cohen WN, Denbesten L: Cholecystokinin cholangiography and analysis of duodenal bile in the investigation of pain in the right upper quadrant of the abdomen without gallstones.Surg Obstet Gynecol 140:371–376, 1975

    CAS  Google Scholar 

  20. Neschis M, King MC, Murphy RA: Cholecystokinin cholecystography in the diagnosis of acalculous extrahepatic biliary tract disorders.Am J Gastroenterol 70:593–599, 1978

    CAS  PubMed  Google Scholar 

  21. Sykes D: The use of cholecystokinin in diagnosis of biliary pain.Ann R Coll Surg 64:114–116, 1982

    CAS  Google Scholar 

  22. Torsoli A, Ramorino ML, Cocagrande C, Demaio G: Experiments with cholecystokinin.Acta Radiol 55:193–206, 1960

    Google Scholar 

  23. Rosenquist CJ, Barcia TC: Studies of gallbladder contraction using intramuscular Sincalide.Radiology 146:21–23, 1983

    CAS  PubMed  Google Scholar 

  24. Sargent EN, Boswell W, Hubscher J: Cholecystokinetic cholecystography: efficiency and tolerance studies of Ceruletide.AJR 130:1051–1055, 1978

    CAS  PubMed  Google Scholar 

  25. Harvey RF, Rad AE: Effect of cholecystokinin on colonic mobility and symptoms in patients with the irritable bowel syndrome.Lancet 1:1–3, 1973

    CAS  PubMed  Google Scholar 

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Morewood, D.J.W., Whitehouse, G.H. Assessment of gallbladder function using ceruletide in oral cholecystography. Gastrointest Radiol 10, 97–105 (1985). https://doi.org/10.1007/BF01893080

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  • DOI: https://doi.org/10.1007/BF01893080

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