Levels of 17-hydroxycorticosteroids in blood plasma of rhesus monkeys and hamadry as baboons and changes caused by neuro-emotional action

  • N. P. Goncharov
Biochemistry and Biophysics

Summary

Experiments were made by Porter and Silber's method in N. A. Yudaev and Yu. A. Pankov's modification to establish the normal level of 17-hydroxycorticosteroids in the blood plasma of monkeys. The concentration of 17-hydroxycorticosteroids in male rhesus macaques was on the average 34±1.3 mg %, in females −44±1.2 mg %; in male and female hamadryads −41±1.5 mg % and 52±1.5 mg % respectively.

Variable reaction of the adrenal cortex to intravenous injection of ACTH was found in different species of monkeys, in rhesus macaques the maximum increase in the amount of 17-hydroxycorticosteroids was registered one hour after the injection of the preparation, in hamadryads-in two hours.

Nembutal anesthesis presents the development of the stress condition. It was found that the neuro-emotional strain in monkeys brings about a marked increase in the hormonal function of the adrenal cortex.

Keywords

Internal Medicine Stress Condition Normal Level Intravenous Injection Blood Plasma 

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Copyright information

© Consultants Bureau 1966

Authors and Affiliations

  • N. P. Goncharov
    • 1
  1. 1.Institute of Experimental Pathology and TherapyAcademy of Medical Sciences of the USSRSukhumi

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