Summary
Blocking of the synthesis of information RNA on DNA with the antibiotic aurantine considerably reduces the activation of the lipolytic enzymes in the connective tissue cells in response to injection of lipids. This is evidence that a substrate-induced synthesis of enzymes takes part in the mechanism of intensification of the activity of lipolytic enzymes in response to injection of lipids.
Data on the inducibility of lipolytic enzymes demonstrate their high adaptational capacity, i. e., the ability of a given enzymatic system to adapt itself to the body requirements by means of extensive and flexible variations in synthesis.
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Leites, F.L., Fuks, B.B. On the mechanism of increasing the activity of lipolytic enzymes upon the injection of lipids into tissues. Bull Exp Biol Med 61, 516–520 (1966). https://doi.org/10.1007/BF01892442
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DOI: https://doi.org/10.1007/BF01892442