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Suppression of contact hypersensitivity by ultraviolet radiation: An experimental model

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References

  1. Asherson GL, Zembala M, Barnes RMR (1971) The mechanism of immunological unresponsiveness to picryl chloride and the possible role of antibody mediated depression. Clin Exp Immunol 9: 111

    PubMed  Google Scholar 

  2. Daynes RA, Schmitt MK, Roberts LK, Spellman CW (1979) Phenotypic and physical characteristics of the lymphoid cells involved in the immunity to syngeneic UV-induced tumors. J Immunol 122: 2458

    PubMed  Google Scholar 

  3. DeFabo EC (1974) An action spectrum between 260 nm and 800 nm for the photoinduction of carotenoid synthesis inNeurospora crassa. Ph. D. Thesis, George Washington University, Washington, D. C.

    Google Scholar 

  4. DeFabo EC, Kripke ML (1979) Dose-response characteristics of immunologic unresponsiveness to UV-induced tumors produced by UV irradiation of mice. Photochem Photobiol 30: 385

    PubMed  Google Scholar 

  5. DeFabo EC, Kripke ML (1980) Wavelength dependence and dose-rate independence of UV radiation-induced immunologic unresponsiveness of mice to a UV-induced fibrosarcoma. Photochem Photobiol 32: 183

    PubMed  Google Scholar 

  6. Everett MA, Yeargers E, Sayre RM, Olson RL (1966) Penetration of epidermis by ultraviolet rays. Photochem Photobiol 5: 533

    PubMed  Google Scholar 

  7. Fisher MS, Kripke ML (1977) Systemic alteration induced in mice by ultraviolet light irradiation and its relationship to ultraviolet carcinogenesis. Proc Natl Acad Sci USA 74: 1688

    PubMed  Google Scholar 

  8. Fisher MS, Kripke ML (1978) Further studies on the tumor-specific suppressor cells induced by ultraviolet radiation. J Immunol 121: 1139

    PubMed  Google Scholar 

  9. Greene MI, Sy MS, Kripke ML, Benacerraf B (1979) Impairment of antigen-presenting cell function by ultraviolet radiation. Proc Natl Acad Sci USA 76: 6592

    Google Scholar 

  10. Haniszko J, Suskind RR (1963) The effect of ultraviolet radiation on experimental cutaneous sensitization in guinea pigs. J Invest Dermatol 40: 183

    PubMed  Google Scholar 

  11. Horowitz S, Cripps D, Hong R (1974) Selective T cell killing of human lymphocytes by ultraviolet radiation. Cell Immunol 14: 80

    PubMed  Google Scholar 

  12. Ishizaka K, Adachi R (1976) Generation of specific helper cells and suppressor cells in vitro for the IgE and IgG antibody responses. J Immunol 117: 40

    PubMed  Google Scholar 

  13. Jessup JM, Hanna N, Palaszynski E, Kripke ML (1978) Mechanisms of depressed reactivity to dinitrochlorobenzene and ultraviolet-induced tumors during ultraviolet carcinogenesis in BALB/c mice. Cell Immunol 38: 105

    PubMed  Google Scholar 

  14. Kripke ML (1974) Antigenicity of murine skin tumors induced by ultraviolet light. J Natl Cancer Inst 53: 1333

    PubMed  Google Scholar 

  15. Kripke ML (1976) Target organ for a systemic effect of UV radiation. Photochem Photobiol 24: 599

    PubMed  Google Scholar 

  16. Kripke ML (1980) Effects of UV radiation on the immune system: Consequences for UV carcinogenesis. In Escobar M, Friedman H (eds) Macrophages and lymphocytes, Part A. Plenum Press, New York, p 589

    Google Scholar 

  17. Kripke ML, Fisher MS (1976) Immunologic parameters of ultraviolet carcinogenesis. J Natl Cancer Inst 57: 211

    PubMed  Google Scholar 

  18. Kripke ML, Lofgreen JS, Beard J, Jessup JM, Fisher MS (1977) In vivo immune responses of mice during carcinogenesis by ultraviolet radiation. J Natl Cancer Inst 59: 1227

    PubMed  Google Scholar 

  19. Kripke ML, Thorn RM, Lill PH, Civin CI, Pazmiño NH, Fisher MS (1979) Further characterization of immunologic unresponsiveness induced in mice by UV radiation: Growth and induction of nonUV-induced tumors in UV-irradiated mice. Transplantation 28: 212

    PubMed  Google Scholar 

  20. Letvin NL, Fox IJ, Greene MI, Benacerraf B, Germain RN (1980) Immunologic effects of whole body ultraviolet (UV) irradiation. II. Defect in splenic adherent cell antigen presentation for stimulation of T cell proliferation. J Immunol 125: 1402

    PubMed  Google Scholar 

  21. Letvin NL, Greene MI, Benacerraf B, Germain RN (1980) Immunologic effects of whole body ultraviolet (UV) irradiation: Selective defect in splenic adherent cell function in vitro. Proc Natl Acad Sci USA 77: 2881

    PubMed  Google Scholar 

  22. Letvin NL, Nepom JT, Greene MI, Benacerraf B, Germain RN (1980) Loss of Ia-bearing splenic adherent cells after whole body ultraviolet irradiation. J Immunol 125: 2550

    PubMed  Google Scholar 

  23. Levis WR, Lincoln PM, Dattner AM (1978) Effect of ultraviolet light on dinitrochlorobenzene specific antigen-presenting function. J Immunol 121: 1496

    PubMed  Google Scholar 

  24. Morison WL, Parrish JA, Woehler MA, Bloch KJ (1981) The influence of ultraviolet radiation on allergic contact dermatitis in the guinea pig. I. UVB radiation. Br J Dermatol 104: 161

    PubMed  Google Scholar 

  25. Noonan FP, Pedersen G, Kripke M (1980) Ultraviolet radiation suppresses cell-mediated immunity. J Invest Dermatol 74: 261

    Google Scholar 

  26. Noonan FP, Kripke ML, Pedersen GM, Greene MI (1981) Suppression of contact hypersensitivity in mice by ultraviolet radiation is associated with defective antigen presentation. Immunology, in press.

  27. Norbury KC, Kripke ML, Budmen MB (1977) In vitro reactivity of macrophages and lymphocytes from UV-irradiated mice. J Natl Cancer Inst 59: 1231

    PubMed  Google Scholar 

  28. Pierres M, Germain RN (1978) Antigen-specific T cell-mediated suppression IV. Role of macrophages in generation of L-glutamic acid-L-alanine-L-tyrosine (GAT)-specific suppressor T cells in responder mouse strains. J Immunol 121: 1306

    PubMed  Google Scholar 

  29. Spellman CW, Daynes RA (1977) Modification of immunologic potential by ultraviolet radiation. II. Generation of suppressor cells in short-term UV-irradiated mice. Transplantation 24: 120

    PubMed  Google Scholar 

  30. Spellman CW, Woodward JG, Daynes RA (1977) Modification of immunologic potential by ultraviolet radiation. I. Immune status of short-term UV-irradiated mice. Transplantation 24: 112

    PubMed  Google Scholar 

  31. Stingl G, Katz SI, Shevach EM, Rosenthal AS, Green I (1978) Analogous functions of macrophages and Langerhans cells in the initiation of the immune response. J Invest Dermatol 71: 59

    PubMed  Google Scholar 

  32. Toews GB, Bergstresser PR, Streilein JW (1980) Epidermal Langerhans cell density determines whether contact hypersensitivity or unresponsiveness follows skin painting with DNFB. J Immunol 124: 445

    PubMed  Google Scholar 

  33. Vadas MA, Miller JFAP, Whitelaw A, Gamble J (1977) Regulation by the H-2 gene complex of delayed-type hypersensitivity. Immunogenetics 4: 137

    Google Scholar 

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Authors and Affiliations

  1. Cancer Biology Program, NCI Frederick Cancer Research Center, P.O. Box B, 21701, Frederick, Maryland, USA

    Frances P. Noonan, Edward C. De Fabo & Margaret L. Kripke

Authors
  1. Frances P. Noonan
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  2. Edward C. De Fabo
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  3. Margaret L. Kripke
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Noonan, F.P., De Fabo, E.C. & Kripke, M.L. Suppression of contact hypersensitivity by ultraviolet radiation: An experimental model. Springer Semin Immunopathol 4, 293–304 (1981). https://doi.org/10.1007/BF01892183

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