Skip to main content
Log in

The contribution of ultrasonography and computed tomography in the diagnosis of nonfunctioning islet cell tumors of the pancreas

  • Published:
Gastrointestinal Radiology Aims and scope Submit manuscript

Abstract

The personal series of 12 nonfunctioning islet cell tumors (NFIT) of the pancreas is reported. The ultrasound and computed tomography features of NFIT are analyzed, and a few signs are identified that may be useful in the differential diagnosis vs ductal carcinoma. The necessity to complete the diagnostic work up by means of fine needle aspiration biopsy and cytologic smears is also emphasized.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Kent RB III, Van Heerden JA, Weiland LH: Nonfunctioning islet cell tumors.Ann Surg 193:185–190, 1981

    Google Scholar 

  2. Broder LE, Carter SK: Pancreatic islet cell carcinoma. I. Clinical features of 52 patients.Ann Intern Med 79:101–107, 1973

    Google Scholar 

  3. Cubilla AL, Hajdu SI: Islet cell carcinoma of the pancreas.Arch Pathol Lab Med 99:204–207, 1975

    Google Scholar 

  4. Dial PF, Braasch JW, Rossi RL, Lee AK, Jin G: Management of nonfunctioning islet cell tumors of the pancreas.Surg Clin North Am 65:291–299, 1985

    Google Scholar 

  5. Broughan TA, Leslie JD, Soto JM, Hermann RE: Pancreatic islet cell tumors.Surgery 99:671–678, 1986

    Google Scholar 

  6. Eelkema EA, Stephens DH, Ward EM, Sheedy PF II: CT features of nonfunctioning islet cell carcinoma.AJR 143:943–948, 1984

    Google Scholar 

  7. Eckhauser FE, Cheung PS, Vinik AI, Strodel WE, Lloyd RV, Thompson NW: Nonfunctioning malignant neuroendocrine tumors of the pancreas.Surgery 100:978–988, 1986

    Google Scholar 

  8. Hancke S: Localization of hormone-producing gastrointestinal tumours by ultrasonic scanning.Scand J Gastroenterol 14 (suppl 53):115–116, 1979

    Google Scholar 

  9. Dunnick NR, Doppman JL, Mills SR, McCarthy DM: Computed tomographic detection of nonbeta pancreatic islet cell tumors.Radiology 135:117–120, 1980

    Google Scholar 

  10. Kuhn FP, Günther RW, Rückert K, Beyer J: Ultrasonic demonstration of small pancreatic islet cell tumors.J Clin Ultrasound 10:173–175, 1982

    Google Scholar 

  11. Günther RW, Klose KJ, Rückert K, Kuhn FP, Beyer J, Klotter HJ, Cordes U: Islet-cell tumors: detection of small lesions with computed tomography and ultrasound.Radiology 148:485–488, 1983

    Google Scholar 

  12. Krudy AG, Doppman JL, Jensen RT, Norton JA, Collen MJ, Shawker TH, Gardner JD, McArthur K, Gorden P: Localization of islet cell tumors by dynamic CT: comparison with plain CT, arteriography, sonography, and venous sampling.AJR 143:585–589, 1984

    Google Scholar 

  13. Günther RW, Klose KJ, Rückert K, Beyer J, Kuhn FP, Klotter HJ: Localization of small islet-cell tumors: preoperative and intraoperative ultrasound, computed tomography, arteriography, digital subtraction angiography, and pancreatic venous sampling.Gastrointest Radiol 10:145–152, 1985

    Google Scholar 

  14. Breatnach ES, Han SY, Rahatzad MT, Stanley RJ: CT evaluation of glucagonomas.JCAT 9:25–29, 1985

    Google Scholar 

  15. Rossi P, Baert A, Passariello R, Simonetti G, Pavone P, Tempesta P: CT of functioning tumors of the pancreas.AJR 144:57–60, 1985

    Google Scholar 

  16. Gorman B, Charboneau JW, James EM, Reading CC, Galiber AK, Grant CS, Van Heerden JA, Telander RL, Service FJ: Benign pancreatic insulinoma: preoperative and intraoperative sonographic localization.AJR 147:929–934, 1986

    Google Scholar 

  17. Galiber AK, Reading CC, Charboneau JW, Sheedy PF II, James EM, Gorman B, Grant CS, Van Heerden JA, Telander RL: Localization of pancreatic insulinoma: comparison of pre- and intraoperative US with CT and angiography.Radiology 166:405–408, 1988

    Google Scholar 

  18. Stark DD, Moss AA, Goldberg HI, Deveney CW: CT of pancreatic islet cell tumors.Radiology 150:491–494, 1984

    Google Scholar 

  19. Kolmannskog F, Schrumpf E, Vaines K: Computed tomography and angiography in pancreatic apudomas and cystadenomas.Acta Radiol (Diagnosis) 23:365–372, 1982

    Google Scholar 

  20. Gold J, Rosenfield AT, Sostman D, Burrell M, Taylor KJW: Nonfunctioning islet cell tumors of the pancreas: radiographic and ultrasonographic appearances in two cases.AJR 131:715–717, 1978

    Google Scholar 

  21. Frija J, Schmit P, Vadrot D, Katz M, Laval-Jeantet M: Non-secreting islet cell adenoma of the pancreas evaluated by computed tomography and sonography. Report of a case.Eur J Radiol 2:160–161, 1982

    Google Scholar 

  22. Stewart R, Sirinek KR, Levine BA: The asymptomatic pancreatic islet cell tumor: a novel presentation.Surgery 100:108–112, 1986

    Google Scholar 

  23. Cohen DJ, Fagelman D: Pancreas islet cell carcinoma with complete fatty replacement: CT characteristics.JCAT 10:1050–1051, 1986

    Google Scholar 

  24. Gudjonsson B: Cancer of the pancreas. 50 years of surgery.Cancer 60:2284–2303, 1987

    Google Scholar 

  25. Moertel CG, Hanley JA, Johnson LA: Streptozocin alone compared with streptozocin plus fluorouracil in the treatment of advanced islet cell carcinoma.New Engl J Med 303:1189–1194, 1980

    Google Scholar 

  26. Torrisi JR, Treat J, Zeman R, Dritschilo A: Radiotherapy in the management of pancreatic islet cell tumors.Cancer 60:1226–1231, 1987

    Google Scholar 

  27. Adler O, Kaftori JK, Rosenberger A, Ben Arieh J: Non-functioning islet cell tumours of the pancreas. A review of radiological literature and a report on two cases.Röfo 127:559–563, 1977

    Google Scholar 

  28. Fugazzola C, Bergamo Andreis IA, Portuese A, Procacci C, Iacono C, Jannucci A, Cinquino M, Della Sala S, Mansueto G: Tumori cistici del pancreas. Apporto diagnostico dell'ecografia e della tomografia computerizzata. In: Rizzatto G Solbiati L Derchi L Busilacchi P (eds):Imaging-US, Avanzamenti '88 Milano: Masson, 1989, pp 119–129

    Google Scholar 

  29. Friedman AC, Lichtenstein JC, Fishman EK, Oertel JE, Dachman AH, Siegelman SS: Solid and papillary epithelial neoplasm of the pancreas.Radiology 154:333–337, 1985

    Google Scholar 

  30. Weiland LH: Frozen section diagnosis in tumors of the pancreas.Sem Diagn Pathol 1:54–58, 1984

    Google Scholar 

  31. Hsiu JG, D'Amato NA, Sperling MH, Greenspan M, Jaffe AH, Smith R III, De La Torre R: Malignant islet-cell tumor of the pancreas diagnosed by fine needle aspiration biopsy. A case report.Acta Cytol 29:576–579, 1985

    Google Scholar 

  32. Larsson LI: Endocrine pancreatic tumors.Human Pathol 9:401–416, 1978

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Fugazzola, C., Procacci, C., Andreis, I.A.B. et al. The contribution of ultrasonography and computed tomography in the diagnosis of nonfunctioning islet cell tumors of the pancreas. Gastrointest Radiol 15, 139–144 (1990). https://doi.org/10.1007/BF01888758

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01888758

Key words

Navigation