Skip to main content
SpringerLink
Log in

Ungleiches Crossing-over als mögliche Ursache blutgruppenserologischer Phänomene

Unusual serogenetic observations possibly due to unequal crossing-over

  • Originalarbeiten
  • Published:
Zeitschrift für Rechtsmedizin Aims and scope Submit manuscript

Summary

The mechanism of unequal chromosomal crossing-over is explained. Serologic pitfalls, which might be due to this abnormal genetic event, are demonstrated in the blood group systems ABO, HLA, Gm, and Rhesus.

Zusammenfassung

Das Prinzip des ungleichen Crossing-ovees wird erläutert. Ungewöhnliche Blutgruppenbefunde in den Systemen AB0, HLA, Gm und Rhesus, die sich durch diese genetische Besonderheit erklären lassen, weisen auf seltene Fehlinterpretationsmöglichkeiten bei der Abstammungsbegutachtung hin.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literatur

  1. Boettcher B (1966) Modification of Bernstein's multiple allele theory for the inheritance of the AB0 blood groups in the light of modern genetical concepts. Vox Sang 11:129–136

    PubMed  Google Scholar 

  2. Bouguerra-Jaquet A, Reviron J, Salmon D, Salmon C (1969) Un exèmple de chromosome cis A1B. Etude thermodynamique de l'antigène B induit. Nouv Rev Fr Hematol 9:392–398

    Google Scholar 

  3. Bush M, Sabo M (1973) Three generations of AB antigens in cis position. Transfusion 13:362

    Google Scholar 

  4. Danilovs JA, Terasaki PI, Kuban DJ, Sparkes RS, Gjertson D, Bernoco D (1979) Two independent HLA-B-locus specificities expressed on a single haplotype. Transplant Proc 11:1722–1725

    PubMed  Google Scholar 

  5. Haselhorst G, Lauer A (1930) Über eine Blutgruppenkombination Mutter AB, Kind 0. Z Konst Forsch 15:205

    Google Scholar 

  6. Haselhorst G, Lauer A (1931) Zur Blutgruppenkombination Mutter AB, Kind 0. Z Konst Forsch 16:227

    Google Scholar 

  7. Hummel, K, Badet J, Bauermeister W, Bender K, Duffner G, Lopez M, Mauff G, Pulverer G, Salmon C, Schmidts W (1977) Inheritance of cis-AB in three generations (family Lam.). Vox Sang 33:290–298

    PubMed  Google Scholar 

  8. Kogure T (1971) A family with unusual inheritance of ABO blood groups. Jpn Jnl Hum Genet 16:69–87

    Google Scholar 

  9. Kossovitch N (1929) Les groupes sanguins des français et les règles de l'hérédité. Rev Anthropol 39:374

    Google Scholar 

  10. Loghem E van (1979) Genetic markers of immunoglobulins. 8. Internationale Tagung der Gesellschaft für forensische Blutgruppenkunde (London), S 89–104

  11. Loghem E van, Lange G de, Leeuwen AM van, Eede PH van, Nijenhuis LE, Lefranc M-P, Lefranc G (1982) Human IgG allotypes co-occurring in more than one IgG subclass. Vox Sang (im Druck)

  12. Lopez M, Banopoulos H, Liberge G, Salmon C (1975) A cold autoagglutinin of anti-B specificity in an A1B patient. Vox Sang 28:371–375

    PubMed  Google Scholar 

  13. Lopez M (1976) Le groupe sanguin cis AB. Etude quantitative et qualitative des antigènes ABH. Rev Fr Transfus Immunohematol 19:117

    PubMed  Google Scholar 

  14. Madsen G, Heistö H (1968) A Korean family showing inheritance of A and B on the same chromosome. Vox Sang 14:211–217

    PubMed  Google Scholar 

  15. Mouellec J, Le Chevrel P (1959) A rare variant of B in a human blood sample belonging to group AB. Nature 183:1733

    Google Scholar 

  16. Mouellec J, Le Chevrel P (1959) Un facteur B faible dans un sang du groupe AB. Transfusion (Paris) 2:47–56

    Google Scholar 

  17. Reviron J, Jaquet A, Delarue F, Liberge G, Salmon D, Salmon C (1967) Interactions alléliques des gènes de groupes sanguins AB0. Résultat préliminaires avec l'anti-B d'un sujèt cis AB et étude quantitative avec l'anti-B d'un sujèt A10. Nouv Rev Fr Hematol 7:425–433

    PubMed  Google Scholar 

  18. Sachs HW, Reuter W, Tippett P, Gavin J (1978) An Rh gene complex producing both CW and c antigen. Vox Sang 35:272–274

    PubMed  Google Scholar 

  19. Seyfried H, Walewska I, Werblinska B (1964) Unusual inheritance of AB0 group in a family with weak B antigens. Vox Sang 9:268–277

    Google Scholar 

  20. Sturtevant AH (1925) The effects of unequal crossing over at thebar locus in Drosophila. Genetics 10:117

    Google Scholar 

  21. Vogel F, Motulsky AG (1979) Human genetics: Problems and approaches. Springer, Berlin Heidelberg New York

    Google Scholar 

  22. Yamaguchi H, Okubo Y, Hazama F (1965) An A2B3 phenotype blood showing atypical mode of inheritance. Proc Imp Acad Jpn 41:316–320

    Google Scholar 

  23. Yamaguchi H, Okubo Y, Hazama F (1966) Another Japanese A2B3 blood-group family with the propositus having a group 0 father. Proc Imp Acad Jpn 42:517–520

    Google Scholar 

  24. Yamaguchi H, Okuho Y, Tanaka M (1970) ‘Cis AB’ bloods found in Japanese families. Jpn Jnl Hum Genet 15:198–215

    Google Scholar 

  25. Yoshida A, Yamaguchi H, Okubo Y (1980a) Genetic mechanism of cis-AB inheritance. I. A case associated with unequal chromosomal crossing-over. Am J Hum Genet 32:332–338

    PubMed  Google Scholar 

  26. Yoshida A, Yamaguchi H, Okubo Y (1980b) Genetic mechanism of cis-AB inheritance. II. Cases associated with structural mutation of blood group glycosyltransferase. Am J Hum Genet 32:645–650

    PubMed  Google Scholar 

  27. Yoshida A, Yamato K, Dave V, Yamaguchi H, Okubo Y (1982) A case of weak blood group B expression (Bm) associated with abnormal blood group galactosyltransferase. Blood 59:323–327

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institut für Rechtsmedizin der Universität Düsseldorf, Moorenstraße 5, D-4000, Düsseldorf 1, Bundesrepublik Deutschland

    J. Henke & M. Basler

Authors
  1. J. Henke
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. Basler
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Herrn Prof. Dr. F. Schleyer anläßlich seines 70. Geburtstages gewidmet

Rights and permissions

Reprints and permissions

About this article

Cite this article

Henke, J., Basler, M. Ungleiches Crossing-over als mögliche Ursache blutgruppenserologischer Phänomene. Z Rechtsmed 90, 27–33 (1983). https://doi.org/10.1007/BF01886064

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01886064

Key words

Schlüsselwörter

Search

Navigation