Skip to main content
Log in

Tödliche Vergiftung mit Acebutolol (Prent)

Lethal Intoxication by Acebutolol

  • Kasuistik
  • Published:
Zeitschrift für Rechtsmedizin Aims and scope Submit manuscript

Summary

Report on suicidal intoxication by acebutolol (prent). Thin-layer and gas chromatography as well as spectrophotometry were used to show the presence of and to determine acebutolol and its aniline derivative arising from hydrolysis in all tissues. The highest concentrations were found in urine and liver.

Zusammenfassung

Bericht über eine suicidale Vergiftung mit Acebutolol (Prent). Durch dünnschicht- und gaschromatographische sowie spektrophotometrische Untersuchungen konnten Acebutolol und das durch Hydrolyse entstehende Anilinderivat in allen Asservaten nachgewiesen und bestimmt werden. Die höchsten Konzentrationen fanden sich im Harn und in der Leber.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literatur

  1. Klug, E.: Ultraschallextraktion biologischer Proben. Beitr. Gerichtl. Med.28, 333 (1971)

    Google Scholar 

  2. Osselton, M. D.: The release of basic drugs by the enzymic digestion of tissues in cases of poisoning. J. Forens. Sci. Soc.17, 189 (1977)

    Google Scholar 

  3. Bratton, A. C., Marshall, E. K.: A new coupling component for sulfanilamide determination. J. Biol. Chem.128, 538 (1939)

    Google Scholar 

  4. Z.B. Bonse, G., Metzler, M.: Biotransformationen organischer Fremdsubstanzen. Stuttgart 1978

  5. Robinson, R.: TIAFT 1973. Persönliche Mitteilung

  6. Turner, J. E., Carvey, R. H.: A fatal case involving propranolol and codeine. Clin. Toxicol.8, 271 (1975)

    PubMed  Google Scholar 

  7. Piper, N., Smith, D.: TIAFT 1976. Persönliche Mitteilung

  8. Alha, A., Korte, T., Koskinen, K.: TIAFT 1976. Persönliche Mitteilung

  9. Dickson, S. J., Muirhead, J. M., Nelson, P. E.: The gas chromatographic determination of alprenolol in human postmortem liver and blood samples. J. Anal. Toxicol.2, 242 (1978)

    Google Scholar 

  10. Oliver, J. S., Watson, A. A.: Oxprenolol (Transicor) poisoning. Med. Sci. Law17, 279 (1977)

    PubMed  Google Scholar 

  11. Harzer, K.: Tödliche Vergiftung mit Acebutolol (Prent). Toxichem. 7 (1979)

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Klug, E., Schneider, V. Tödliche Vergiftung mit Acebutolol (Prent). Z Rechtsmed 83, 325–330 (1979). https://doi.org/10.1007/BF01882179

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01882179

Key words

Schlüsselwörter

Navigation