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Fluorescent nucleoside derivatives: Luminescence study of 4-dimethylaminopyridinium chloride derived from guanosine

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Abstract

Photophysical properties of fluorescentN-[2-amino-9-(2′,3′,5′-tri-O-acetyl-β-d-ribofuranosyl)-purin-6-yl]-4-dimethylaminopyridinium chloride (GDMAP) are determined in view of its possible use as a probe in DNA. The fluorescence intensity of GDMAP increases and exhibits doubleexponential decay in the presence of common nucleosides. The formation of ground-state complexes with nucleosides is inferred from absorption and emission measurements.

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References

  1. R. W. Adamiak, E. Biala, and B. Skalaki (1985)Nucleic Acids Res. 13, 2989–3003; (1985)Angew. Chem. Int. Ed. Engl. 24, 1054–1055; G. Wenska, B. Skalski, and Z. Gdaniec (1992)Can. J. Chem. 70, 856–862.

    PubMed  Google Scholar 

  2. B. Skalski, R. P. Steer, and R. E. Verrall (1991).J. Am. Chem. Soc. 113, 1756–1762.

    Google Scholar 

  3. B. Skalski, S. Paszyc, R. W. Adamiak, R. P. Steer, and R. E. Verrall (1990)Can. J. Chem. 68, 2164–2170.

    Google Scholar 

  4. S. Wnuk, B. Skalski, G. Wenska, and R. W. Adamiak, unpublished.

  5. H. Gao, R. Fathi, B. L. Gaffney, B. Goswami, P. Kung, Y. Rhee, R. Jin, and R. A. Jones (1992)J. Org. Chem. 57, 6954–6959.

    Google Scholar 

  6. D. F. Eaton (1988)Pure Appl. Chem. 60, 1107.

    Google Scholar 

  7. D. V. O'Connor and D. Philips (1984)Time-Correlated Single Photon Counting, Academic, London.

    Google Scholar 

  8. D. J. S. Birch, G. Hungerford, and R. E. Imhof (1991)Rev. Sci. Instrum. 62(10), 2405–2408.

    Google Scholar 

  9. J. R. Lakowicz (1983)Principles of Fluorescence Spectroscopy, Plenum Press, New York.

    Google Scholar 

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Wenska, G., Skalski, B., Paszyc, S. et al. Fluorescent nucleoside derivatives: Luminescence study of 4-dimethylaminopyridinium chloride derived from guanosine. J Fluoresc 4, 283–286 (1994). https://doi.org/10.1007/BF01881440

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