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Induction of lipid peroxidation by hexachlorocyclohexane, dieldrin, TCDD, carbon tetrachloride, and hexachlorobenzene in rats

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References

  • Al-Bayati ZAF, Murray WJ, Stohs, SJ (1987) 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced lipid peroxidation in hepatic and extrahepatic tissues of male and female rats. Arch Environ Contam Toxicol 15:159–166

    Google Scholar 

  • Al-Bayati ZAF, Stohs SJ (1987) The role of iron in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced lipid peroxidation by rat liver microsomes. Toxicol Lett 38:115–121

    PubMed  Google Scholar 

  • Alleman MA, Koster JF, Wilson JHP, Edixhoven-Bosdijk A, Slee RG, Kroos MJ and Van Eijk HG (1985). The involvement of iron and lipid peroxidation in the pathogenesis of HCB induced porphyria. Biochem Pharmacol 34:161–166

    PubMed  Google Scholar 

  • Bach D and Sela BA (1984) Interaction of the chlorinated hydrocarbon insecticide lindane or DDT with lipids — A differential scanning calorimetry study. Biochem Pharmacol 33:2227–2230

    PubMed  Google Scholar 

  • Blekkenhorst GH, Day RS, Eales L (1980) The effect of bleeding and iron administration on the development of hexachlorobenzene-induced rat porphyria. Int J Biochem 12:1013–1017

    PubMed  Google Scholar 

  • Campbell MA, Gyorkos J, Leece B, Homonko K, Safe S (1983) The effects of twenty-two organochlorine pesticides as inducers of the hepatic drug-metabolizing enzymes. Gen Pharmacol 14:445–454

    PubMed  Google Scholar 

  • Chadwick RW, Cppeland MF, Froehlich R, Cooke N (1983) Chlorobenzene-impaired lindane metabolism and the effect of pretreatment with chlorobenzene, lindane, or chlorobenzene plus lindane. J Toxicol Environ Hlth 12:559–610

    Google Scholar 

  • Haake JE, Kelley M, Keys B, Safe S (1987) The effects of organochlorine pesticides as inducers of testosterone and benzo(a)pyrene hydroxylases. Gen Rharmacol 18:165–169

    Google Scholar 

  • Innami S, Ono S, Nakamura A, Ikegami S, Nagayama S, Nishide E (1979) Effect of polychlorinated biphenyls (PCB) on lipid peroxide formation in rats. Fukuoka Acta Med 70:102–108

    PubMed  Google Scholar 

  • Junqueira VBC, Simizu K, Videla IA, Barros SB (1986) Dose-dependent study of the effects of acute lindane administration on rat liver Superoxide anion production, antioxidant enzyme activities and lipid peroxidation. Toxicology 41:193–204

    PubMed  Google Scholar 

  • Lowry OH, Rosebrough NJ, Farr WL, Randall RJ (1951) Protein measurement with the folin phenol reagent. J Biol Chem 193:265–275

    PubMed  Google Scholar 

  • Mico BA, Pohl LR (1983) Reductive oxygenation of carbon tetrachloride: Trichloromethylperoxyl radical as possible intermediate in the conversions of carbon tetrachloride to electrophilic chlorine. Arch Biochem Biophys 225:590–609

    Google Scholar 

  • Miles PR, Wright JR, Bowman L, Colby HD (1980) Inhibition of hepatic microsomal lipid peroxidation by drug substrates without drug metabolism. Biochem Pharmacol 29:565–570

    PubMed  Google Scholar 

  • Murphy R, Harvey C (1985) Residues and metabolites of selected persistent halogenated hydrocarbons in blood specimens from a general population survey. Environ Hlth Persp 60:115–120

    Google Scholar 

  • Poland A, and Khutson JC (1982) 2,3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: Examination of the mechanism of toxicity. Ann Rev Pharmacol Toxicol 22:517–554

    Google Scholar 

  • Rappe C, Buser HR, Bosshardt HP (1979) Dioxins, dibenzofurans and other polyhalogenated aromatics: Production, use, formation and destruction. Ann NY Acad Sci 320:1–18

    PubMed  Google Scholar 

  • Rowley B, Sweeney GD (1984) Release of ferrous iron from ferritin by liver microsomes: A possible role in the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin. Can J Biochem Cell Biol 62:1293–1300

    PubMed  Google Scholar 

  • Rozman K, Gorski JR, Rozman P, Parkinson A (1986) Reduced serum thyroid hormone levels in hexachlorobenzene-induced porphyria. Toxicol Lett 30:71–78

    PubMed  Google Scholar 

  • Shara MA, Al-Turk WA, Mohammadpour H, Stohs SJ (1987) Dietary iron and TCDD-induced alterations in hepatic lipid peroxidation, glutathione content and body weight. Drug Chem Tox (in press)

  • Stohs SJ, Al-Bayati ZF, Hassan MQ, Murray WJ, Mohammadpour HA (1986) Glutathione peroxidase and reactive oxygen species in TCDD-induced lipid peroxidation. Adv Exp Med Biol 197:357–365

    PubMed  Google Scholar 

  • Uchiyama M, Mihara M (1978) Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal Biochem 86:271–278

    PubMed  Google Scholar 

  • Viviani A, Iutz WK, Schlatter C (1978) Time course of the induction of aryl hydrocarbon hydroxylase in rat liver nuclei and microsomes by phenobarbital, 3-methylcholanthrene, 2,3,7,8-tetrachlorodibenzo-p-dioxin, dieldrin and other inducers. Biochem Pharmacol 27:2103–2108

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Pharmaceutical Sciences, University of Nebraska Medical Center, 68105-1065, Omaha, Nebraska

    M. R. Goel, M. A. Shara & S. J. Stohs

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  1. M. R. Goel
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  2. M. A. Shara
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  3. S. J. Stohs
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Goel, M.R., Shara, M.A. & Stohs, S.J. Induction of lipid peroxidation by hexachlorocyclohexane, dieldrin, TCDD, carbon tetrachloride, and hexachlorobenzene in rats. Bull. Environ. Contam. Toxicol. 40, 255–262 (1988). https://doi.org/10.1007/BF01881048

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  • DOI: https://doi.org/10.1007/BF01881048

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