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Die Jodinaktivierbarkeit der thyreostimulierenden und exophthalmogenen Wirkung von TSH, LATS, EPF, von Schilddrüsenantikörpern und Serumeiweiß-Franktionen

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Zusammenfassung

TSH, LATS und EPF sind erst bei unphysiologisch hohen Jodidkonzentrationen inaktivierbar, wobei dieser Effekt nicht selektiv diese Eiweißkörper betrifft. Bei gleicher Konzentration werden auch andere Serumeiweiße, vor allemγ-Globuline, verändert. Auch eine unterschiedliche Jodinaktivierbarkeit der thyreostimulierenden und exophthalmogenen Wirkung von TSH ließ sich nicht nachweisen.

Summary

TSH, LATS and EPF are inactivated by iodine in unphysiologically high concentrations. This effect is not specific for these proteins. In the same concentrations other proteins, especially gammaglobulines, are altered, too. Additionally the thyrostimulating and exophthalmogenic effect of TSH is not differently inhibited by iodine.

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Authors and Affiliations

  1. II. Medizinische Klinik und Poliklinik der Universität Kiel, Germany

    K. Schemmel, D. Streich, G. Kreysing, K. Leybold & L. Weisbecker

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  1. K. Schemmel
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  2. D. Streich
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  3. G. Kreysing
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  4. K. Leybold
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  5. L. Weisbecker
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Schemmel, K., Streich, D., Kreysing, G. et al. Die Jodinaktivierbarkeit der thyreostimulierenden und exophthalmogenen Wirkung von TSH, LATS, EPF, von Schilddrüsenantikörpern und Serumeiweiß-Franktionen. Klin Wochenschr 47, 879–883 (1969). https://doi.org/10.1007/BF01879921

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