Biotechnology Techniques

, Volume 2, Issue 4, pp 243–248 | Cite as

Comparison of various methods of KLa estimation in cultures of filamentous microorganisms

  • M. Novák
  • V. Klekner
Measurement and Control


Three methods, the dynamic one, the balance one, and the biological one, were used for KLa estimation in the culture ofAspergillus niger. Big differences between the values obtained by the dynamic and the other two methods were observed. The mathematical model including the diffusion of oxygen into the pellets can offer an explanation.


Oxygen Mathematical Model Filamentous Microorganism 
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Copyright information

© Science & Technology Letters 1988

Authors and Affiliations

  • M. Novák
    • 1
  • V. Klekner
    • 1
  1. 1.Institute of MicrobiologyCzechoslovak Academy of SciencesPragueCzechoslovakia

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