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Rouleau formation of erythrocytes: A dynamical model

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Abstract

A model is presented for the nonBrownian motion of living erythrocytes suspended in their own plasma as observed by Rowlands et al. On the basis of this model, the formation of rouleaux (contractile fibrils among interacting erythrocytes) can be described in terms of an organization of the molecules (mainly fibrinogen) present in blood plasma; this organization is sustained by the nonlinear propagation of electric vibrations generated by red blood cells (coherent electric vibrations of the Fröhlich type).

A number of peculiar experimental features otherwise unexplained can also be taken into account in the framework of the model.

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Authors and Affiliations

  1. Dipartimento di Fisica dell 'Universită, Via Celoria 16, 20133, Milano, (Italy)

    M. Milani

  2. INFN Gruppo IV, Sez. di Milano, Milano, Italy

    E. Del Giudice

  3. Gruppo Nazionale di Struttura della Materia del CNR, Sez. di Milano, Milano, Italy

    S. Doglia

Authors
  1. E. Del Giudice
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  2. S. Doglia
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  3. M. Milani
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Del Giudice, E., Doglia, S. & Milani, M. Rouleau formation of erythrocytes: A dynamical model. J Biol Phys 13, 57–68 (1985). https://doi.org/10.1007/BF01873109

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