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The Journal of Membrane Biology

, Volume 6, Issue 3, pp 259–268 | Cite as

The effect of anions on K+-binding in aHalobacterium species

  • Margaret Ginzburg
  • B. Z. Ginzburg
  • D. C. Tosteson
Article

Summary

Trinitrocresolate (TNC) at a concentration of 2×10−3m brings about rapid loss of K from starvingHalobacterium cells. Higher concentrations of other anions such as salicylate, thiocyanate, and perchlorate produce a similar effect. The TNC-induced K loss is not significantly reversed when TNC is removed from the ambient medium. The rate of K loss in the presence of 2×10−3m TNC is only slightly increased by the temperature in the ranges of 30 to 40°C and 0 to 20°C; between 20 and 30°C, however, the rate increases 10-fold. The K loss was partly replaced by Na+. These data are interpreted in terms of the hypothesis that K is retained in starvingHalobacterium sp. not by active transport, but rather by selective binding on loci which are modified by TNC.

Keywords

Human Physiology Perchlorate Salicylate Active Transport Thiocyanate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York Inc. 1971

Authors and Affiliations

  • Margaret Ginzburg
    • 1
  • B. Z. Ginzburg
    • 1
  • D. C. Tosteson
    • 1
  1. 1.Department of Physiology and PharmacologyDuke University Medical CenterDurham

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