The Journal of Membrane Biology

, Volume 104, Issue 1, pp 1–20 | Cite as

Neutral amino acid transport systems in animal cells: Potential targets of oncogene action and regulators of cellular growth

  • Milton H. SaierJr.
  • Gregory A. Daniels
  • Paula Boerner
  • Joan Lin
Topical Review

Key Words

growth regulation protein kinases nutrient transport tissue culture cells targets of oncogene action regulation 

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References

  1. Adamo, S., Caporale, C., Aguanno, S., Lazdins, J., Faggioni, A., Belli, L., Cortesi, E., Nervi, C., Gastaldi, R., Molinaro, M. 1986.FEBS Lett. 195:352–356Google Scholar
  2. Alitalo, K., Koskinen, P., Mäkelä, T.P., Saksela, K., Sistonen, L., Winqvist, R. 1987.Biochim. Biophys. Acta 907:1–32Google Scholar
  3. Amsler, K., Cook, J.S. 1982.Am. J. Physiol. 242:C94-C101Google Scholar
  4. Amsler, K., Shaffer, C.S., Cook, J.S. 1983.J. Cell. Physiol. 114:184–190Google Scholar
  5. Barber, E.F., Handlogten, M.E., Kilberg, M.S. 1983.J. Biol. Chem. 258:11851–11855Google Scholar
  6. Bass, R., Hedegaard, H.B., Dillehay, L., Moffett, J., Englesberg, E. 1981.J. Biol. Chem. 256:10259–10266Google Scholar
  7. Bhargava, P.M. 1977.J. Theor. Biol. 68:101–137Google Scholar
  8. Blundell, T.L., Bedarkar, S., Humbel, R.E. 1983.Fed. Proc. 42:2592–2597Google Scholar
  9. Boerner, P., Evans-Layng, M., Ü, H.S., Saier, M.H., Jr. 1986.J. Biol. Chem. 261:13957–13962Google Scholar
  10. Boerner, P., Saier, M.H., Jr. 1982a.J. Cell. Physiol. 113:240–246Google Scholar
  11. Boerner, P., Saier, M.H., Jr. 1982b.In: Cold Spring Harbor Conferences on Cell Proliferation. Vol. 9, pp. 555–565. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.Google Scholar
  12. Boerner, P., Saier, M.H., Jr. 1985a.J. Cell. Physiol. 122:308–315Google Scholar
  13. Boerner, P., Saier, M.H., Jr. 1985b.J. Cell. Physiol. 122:316–322Google Scholar
  14. Boyer, P.D., Krebs, E.G., editors. 1986. The Enzymes, 3rd edition. Vol. XVII: Control by Phosphorylation. Part A: General Features, Specific Enzymes (I). Academic Press, Orlando, FloridaGoogle Scholar
  15. Carruthers, A. 1984.Prog. Biophys. Mol. Biol. 43:33–69Google Scholar
  16. Cereijido, M., Robbins, E.S., Dolan, W.J., Rotunno, C.A., Sabatini, D.D. 1978a.J. Cell Biol. 77:853–880Google Scholar
  17. Cereijido, M., Rotunno, C.A., Robbins, E.S., Sabatini, D.D. 1978b Memb. Transp. Proc. 1:433–461Google Scholar
  18. Christensen, H.N. 1964.J. Biol. Chem. 239:3584–3589Google Scholar
  19. Christensen, H.N., Handlogten, M.E. 1981.Biochem. Biophys. Res. Commun. 98:102–107Google Scholar
  20. Christensen, H.N., Liang, M., Archer, E.G. 1967.J. Biol. Chem. 242:5237–5246Google Scholar
  21. Christopher, C.W. 1977.J. Supramol. Struct. 6:485–494Google Scholar
  22. Chuman, L., Fine, L.G., Cohen, A.H., Saier, M.H., Jr. 1982.J. Cell Biol. 94:506–510Google Scholar
  23. Collarini, E.J., Oxender, D.L. 1987.Annu. Rev. Nutr. 7:75–90Google Scholar
  24. Dawson, W.D., Cook, J.S. 1987.J. Cell. Physiol. 132:104–110Google Scholar
  25. Dawson, W.D., Cook, J.S. 1988.In: Membrane Biophysics. III. Biological Transport. M. Dinno and W. McD. Armstrong, editors. pp. 121–133. Alan R. Liss, New YorkGoogle Scholar
  26. Denhardt, D.T., Edwards, D.R., Parfett, C.L.J. 1986.Biochim. Biophys. Acta 865:83–125Google Scholar
  27. Deutscher, J., Saier, M.H., Jr. 1988.Angewandte Chemie (in press) Google Scholar
  28. Dudeck, K.L., Dudenhausen, E.E., Chiles, T.C., Fafournoux, P., Kilberg, M.S. 1987.J. Biol. Chem. 262:12565–12569Google Scholar
  29. Edelman, A.M., Blumenthal, D.K., Krebs, E.G. 1987.Annu. Rev. Biochem. 56:567–613Google Scholar
  30. Englesberg, E., Moffett, J. 1986.J. Membrane Biol. 91:199–212Google Scholar
  31. Erlinger, S., Saier, M.H., Jr. 1982.In Vitro 18:196–202Google Scholar
  32. Fafournoux, P., Rémésy, C., Demigné, C. 1985.Biochem. J. 231:315–320Google Scholar
  33. Fincham, D.A., Mason, D.K., Young, J.D. 1985.Biochem. J. 227:13–20Google Scholar
  34. Foster, D.O., Pardee, A.B. 1969.J. Biol. Chem. 244:2675–2681Google Scholar
  35. Garry, R.F., Bostick, D.A., Ulug, E.T. 1986.Virology 155:378–391Google Scholar
  36. Gazzola, G.C., Dall'Asta, V., Guidotti, G.G. 1981.J. Biol. Chem. 256:3191–3198Google Scholar
  37. Gibbs, E.M., Allard, W.J., Lienhard, G.E. 1986.J. Biol. Chem. 261:16597–16603Google Scholar
  38. Giesen-Crouse, E.M., McRoberts, J.A. 1987.J. Biol. Chem. 262:17393–17397Google Scholar
  39. Guidotti, G.G., Borghetti, A.S., Gazzola, G.C. 1978.Biochim. Biophys. Acta 515:329–366Google Scholar
  40. Handlogten, M.E., Kilberg, M.S. 1984.J. Biol. Chem. 259:3519–3525Google Scholar
  41. Heldin, C.H., Westermark, B. 1984.Cell 37:9–20Google Scholar
  42. Herzlinger, D.A., Easton, T.G., Ojakian, G.K. 1982.J. Cell Biol. 93:269–277Google Scholar
  43. Hyslop, P.A., Kuhn, C.E., Sauerheber, R.D. 1985.Biochem. J. 232:245–254Google Scholar
  44. Hyslop, P.A., Kuhn, C.E., Sauerheber, R.D. 1987.Biochem. Pharmacol. 36:2305–2310Google Scholar
  45. Imhof, B.A., Vollmers, H.P., Goodman, S.L., Birchmeier, W. 1983.Cell 35:667–675Google Scholar
  46. Isselbacher, K.J. 1972.Proc. Natl. Acad. Sci. USA 69:585–589Google Scholar
  47. Johnson, M.A., Weber, M.J. 1979.J. Cell. Physiol. 101:89–100Google Scholar
  48. Johnson, M.A., Weber, M.J. 1980.J. Cell Physiol. 103:363–370Google Scholar
  49. Jonas, A.J., Greene, A.A., Smith, M.L., Schneider, J.A. 1982.Proc. Natl. Acad. Sci. USA 79:4442–4445Google Scholar
  50. Kelley, D.S., Evanson, T., Potter, V.R. 1980.Proc. Natl. Acad. Sci. USA 77:5953–5957Google Scholar
  51. Kiess, W., Haskell, J.F., Lee, L., Greenstein, L.A., Miller, B.E., Aarons, A.L., Rechler, M.M., Nissley, S.P. 1987.J. Biol. Chem. 262:12745–12751Google Scholar
  52. Kikkawa, U., Nishizuka, Y. 1986.Annu. Rev. Cell Biol. 2:149–178Google Scholar
  53. Kilberg, M.S. 1986.Fed. Proc. 45:2438–2454Google Scholar
  54. Kilberg, M.S. 1986.Trends Biochem. Sci. 11:183–186Google Scholar
  55. Kilberg, M.S., Barber, E.F., Handlogten, M.E. 1985.Curr. Top. Cell. Reg. 25:133–163Google Scholar
  56. Kilberg, M.S., Handlogten, M.E., Christensen, H.N. 1980.J. Biol. Chem. 255:4011–4019Google Scholar
  57. Kilberg, M.S., Neuhaus, O.W. 1977.J. Supramol. Struct. 6:191–204Google Scholar
  58. Kleitzien, R.F., Pariza, M.W., Becker, J.E., Potter, V.R., Butcher, F.R. 1976.J. Biol. Chem. 251:3014–3020Google Scholar
  59. Koch, K.S., Leffert, H.L. 1979.Cell 18:153–163Google Scholar
  60. Lagarde, A.E., Franchi, A.J., Paris, S., Pouysségur, J.M. 1988.J. Cell. Biochem. 36:249–260Google Scholar
  61. Lee, S.G., Lipmann, F. 1977.Proc. Natl. Acad. Sci. USA 74:163–166Google Scholar
  62. Leffert, H.L., Koch, K.S. 1985.In: Control of Animal Cell Proliferation. A. Boynton and H.L. Leffert, editors. pp. 367–413. Academic, New YorkGoogle Scholar
  63. Leighton, J., Brada, Z., Estes, L.W., Justh, G. 1969.Science 163:472–473Google Scholar
  64. Lever, J.E. 1979.J. Supramol. Struct. 12:259–272Google Scholar
  65. Lever, J.E., Kennedy, B.G., Vasan, R. 1984.Arch. Biochem. Biophys. 234:330–340Google Scholar
  66. Lobaton, C.D., Moreno, A., Oxender, D.L. 1984.Mol. Cell. Biol. 4:475–483Google Scholar
  67. McRoberts, J.A., Erlinger, S., Rindler, M.J., Saier, M.H., Jr. 1982.J. Biol. Chem. 257:2260–2266Google Scholar
  68. McRoberts, J.A., Taub, M., Saier, M.H., Jr. 1981.In: Functionally Differentiated Cell Lines. G. Sato, editor. pp. 117–139. Alan R. Liss, New YorkGoogle Scholar
  69. McRoberts, J.A., Tran, C.T., Saier, M.H., Jr. 1983.J. Biol. Chem. 258:12320–12326Google Scholar
  70. Mendiaz, E., Mamounas, M., Moffett, J., Englesberg, E. 1986.In Vitro Cell. Dev. Biol. 22:66–74Google Scholar
  71. Misek, D.E., Bard, E., Rodriguez-Boulan, E. 1984.Cell 39:537–546Google Scholar
  72. Misfeldt, D.S., Hamamoto, S.T., Pitelka, D.r. 1976.Proc. Natl. Acad. Sci. USA 73:1212–1216Google Scholar
  73. Moffett, J., Curriden, S., Ertsey, R., Mendiaz, E., Englesberg, E. 1983.Somat. Cell Mol. Genet. 9:189–213Google Scholar
  74. Moffett, J., Englesberg, E. 1986.J. Cell. Physiol. 126:421–429Google Scholar
  75. Moffett, J., Jones, M., Englesberg, E. 1987.Biochemistry 26:2487–2494Google Scholar
  76. Moffett, J., Mendiaz, E., Jones, M., Englesberg, E. 1988.Somat. Cell Mol. Genet. 14 (in press)Google Scholar
  77. Moffett, J., Périer, F., Jones, M., Englesberg, E. 1987.Proc. Natl. Acad. Sci. USA 84:8040–8043Google Scholar
  78. Moore, P.A., Jayme, D.W., Oxender, D.L. 1977.J. Biol. Chem. 252:7427–7430Google Scholar
  79. Moreno, A., Lobaton, C.D., Oxender, D.L. 1985.Biochim. Biophys. Acta 819:271–274Google Scholar
  80. Nilson-Hamilton, M., Hamilton, R.T. 1979.Biochim. Biophys. Acta 588:322–331Google Scholar
  81. Norman, P.S.R., Mann, G.E. 1987.J. Membrane Biol. 96:153–163Google Scholar
  82. Oka, Y., Czech, M.P. 1984.J. Biol. Chem. 259:8125–8133Google Scholar
  83. Oxender, D.L., Lee, M., Cecchini, G. 1977.J. Biol.Chem. 252:2680–2683Google Scholar
  84. Paris, S., Pouysségur, J. 1984.J. Biol. Chem. 259:10989–10994Google Scholar
  85. Pisoni, R.L., Flickinger, K.S., Thoene, J.G., Christensen, H.N. 1987.J. Biol. Chem. 262:6010–6017Google Scholar
  86. Rajendran, V.M., Barry, J.A., Kleinman, J.G., Ramaswamy, K. 1987.J. Biol. Chem. 262:14974–14977Google Scholar
  87. Ratner, L., Josephs, S.F., Wong-Staal, F. 1985.Annu. Rev. Microbiol. 39:419–449Google Scholar
  88. Reznik, V.M., Villela, J., Mendoza, S.A. 1983.J. Cell. Physiol. 117:211–214Google Scholar
  89. Richardson, J.C.W., Simmons, N.L. 1979.FEBS Lett. 105:201–204Google Scholar
  90. Rindler, M.J., Chuman, L.M., Shaeffer, L., Saier, M.H., Jr. 1979.J. Cell Biol. 81:635–648Google Scholar
  91. Rindler, M.J., McRoberts, J.A., Saier, M.H., Jr. 1982.J. Biol. Chem. 257:2254–2259Google Scholar
  92. Rindler, M.J., Saier, M.H., Jr. 1981.J. Biol. Chem. 256:10820–10825Google Scholar
  93. Rindler, M.J., Taub, M., Saier, M.H., Jr. 1979.J. Biol. Chem. 254:11431–11439Google Scholar
  94. Rothenberg, P., Glaser, L., Schlesinger, P., Cassel, D. 1983.J. Biol. Chem. 258:12644–12653Google Scholar
  95. Rozengurt, E. 1980.In: Current Topics in Cellular Regulation. Vol. 17, pp. 59–88. Academic Press, New YorkGoogle Scholar
  96. Rozengurt, E. 1986.Science 234:161–166Google Scholar
  97. Rygaard, J. 1973. Thymus and Self. Immunobiology of the Mouse Mutant Nude. F.A.D.L., Copenhagen, DenmarkGoogle Scholar
  98. Saier, M.H., Jr. 1981.Am. J. Physiol. 240:C106-C109Google Scholar
  99. Saier, M.H., Jr., Boyden, D.A. 1984.Mol. Cell. Biochem. 59:11–32Google Scholar
  100. Saier, M.H., Jr., Erlinger, S., Boerner, P. 1982.In: Membranes in Growth and Development. J.F. Hoffman, editor. pp. 569–597. Alan R. Liss, New YorkGoogle Scholar
  101. Salter, D.W., Baldwin, S.A., Lienhard, G.E., Weber, M.J. 1982.Proc. Natl. Acad. Sci. USA 79:1540–1544Google Scholar
  102. Sharkey, R.G. 1983.Biochim. Biophys. Acta 730:327–341Google Scholar
  103. Shotwell, M.A., Kilberg, M.S., Oxender, D.L. 1983.Biochim. Biophys. Acta 737:267–284Google Scholar
  104. Shotwell, M.A., Mates, P.M., Jayme, D.W., Oxender, D.L. 1982.J. Biol. Chem. 257:2974–2980Google Scholar
  105. Shotwell, M.A., Oxender, D.L. 1983.Trends Biochem. Sci. 8:314–316Google Scholar
  106. Simmons, K., Fuller, S.D. 1985.In: Animal Review of Cell Biology. Vol. 1, pp. 243–288. Palo Alto, CaliforniaGoogle Scholar
  107. Skaper, S.D., Montz, H.P.M., Varon, S. 1986.Brain Res. 386:130–135Google Scholar
  108. Skaper, S.D., Varon, S. 1987.J. Cell. Physiol. 130:453–459Google Scholar
  109. Stiles, C.D., Desmond, W., Chuman, L.M., Sato, G., Saier, M.H., Jr. 1976a.Cancer Res. 36:1353–1360Google Scholar
  110. Stiles, C.D., Desmond, W., Chuman, L.M., Sato, G., Saier, M.H., Jr. 1976b.Cancer Res. 36:3300–3305Google Scholar
  111. Stiles, C.D., Roberts, P.E., Saier, M.H., Jr., Sato, G. 1977.In: Modern Trends in Human Leukemia II. R. Neth, R.C. Gallo, K. Mannweiler, and W.C. Maloney, editors. pp. 185–194. Lehmanns, MunchenGoogle Scholar
  112. Taub, M. 1984a.In: Mammalian Cell Culture. J. P. Mather, editor. pp. 129–150. Plenum, New YorkGoogle Scholar
  113. Taub, M. 1984b.In: Methods for Serum-free Culture of Epithelial and Fibroblastic Cell, D.W. Barnes, D.A. Sirbasku, and G.H. Sato, editors. pp. 3–24. Alan R. Liss, New YorkGoogle Scholar
  114. Taub, M., Saier, M.H., Jr. 1979.J. Biol. Chem. 254:11440–11444Google Scholar
  115. Taub, M., Chuman, L., Saier, M.H., Jr., Sato, G. 1979.Proc. Natl. Acad. Sci. USA 76:3338–3342Google Scholar
  116. Taub, M., Devis, P.E., Grohol, S.H. 1984.J. Cell. Physiol. 120:19–28Google Scholar
  117. Taub, M., Saier, M.H., Jr., Chuman, L., Hiller, S. 1983.J. Cell. Physiol. 114:153–161Google Scholar
  118. Taub, M., Ü, B., Chuman, L., Rindler, M.J., Saier, M.H., Jr., Sato, G. 1981.J. Supramol. Struct. Cell. Biochem. 15:63–72Google Scholar
  119. Ü, H.S., Saier, M.H., Jr., Ellisman, M.H. 1979.Exp. Cell Res. 122:384–390Google Scholar
  120. Ü, H.S., Saier, M.H., Jr., Ellisman, M.H. 1980.Exp. Cell Res. 128:223–235Google Scholar
  121. Ü, H.S., Boerner, P., Rindler, M., Chuman, L., Saier, M.H., Jr. 1985.J. Cell. Physiol. 122:299–307Google Scholar
  122. Ulug, E.T., Garry, R.F., Waite, M.R.F., Bose, H.R., Jr. 1984.Virology 132:118–130Google Scholar
  123. Varon, S., Skaper, S.D. 1983.Trends Biochem. Sci. 8:22–25Google Scholar
  124. Vidaver, G.A. 1964.Biochemistry 3:662–667Google Scholar
  125. Vigne, P., Frelin, C., Lazdunski, M. 1984.EMBO J. 3:1865–1870Google Scholar
  126. Weber, M.J., Evans, P.K., Johnson, M.A., Nakamura, K.D., Salter, D.W. 1984.Fed. Proc. 43:101–106Google Scholar
  127. White, M.K., Bramwell, M.E., Harris, H. 1981.Nature (London) 294:232–235Google Scholar
  128. Yeh, L.A., Ling, L., English, L., Cantley, L. 1983.J. Biol. Chem. 258:6567–6574Google Scholar

Copyright information

© Springer-Verlag New York Inc 1988

Authors and Affiliations

  • Milton H. SaierJr.
    • 1
  • Gregory A. Daniels
    • 1
  • Paula Boerner
    • 1
  • Joan Lin
    • 1
  1. 1.Department of Biology, C-016The University of California, San Diegola Jolla

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