Skip to main content

Amiloride and its analogs as tools in the study of ion transport

The Journal of Membrane Biology volume 105, pages 1–21 (1988)Cite this article

This is a preview of subscription content, access via your institution.

Access options

Buy single article

Instant access to the full article PDF.

43,34 €

Price includes VAT (Finland)
Tax calculation will be finalised during checkout.

References

  1. Aronson, P.S., Nee, J., Shum, M.A. 1982.Nature (London) 299:161–163

    Google Scholar 

  2. Barby, P., Chassande, O., Vigne, P., Frelin, C., Ellory, C., Cragoe, E.J., Jr., Lazdunski, M. 1987.Proc. Natl. Acad. Sci. USA 84:4836–4840

    Google Scholar 

  3. Benos, D.J. 1982.Am. J. Physiol. 242:C131-C145

    Google Scholar 

  4. Benos, D.J., Reyes, J., Shoemaker, D.G. 1983.Biochim. Biophys. Acta 734:99–104

    Google Scholar 

  5. Benos, D.J., Saccomani, G., Brenner, B.M., Sariban-Sohraby, S. 1986.Proc. Natl. Acad. Sci. USA 83:8525–8529

    Google Scholar 

  6. Benos, D.J., Saccomani, G., Sariban-Sohraby, S. 1987.J. Biol. Chem. 262:10613–10618

    Google Scholar 

  7. Benos, D.J., Simon, S.A., Mandel, L.J., Cala, P.M. 1976.J. Gen. Physiol. 68:43–63

    Google Scholar 

  8. Bently, P.J. 1968.J. Physiol. (London) 195:317–330

    Google Scholar 

  9. Besterman, J.M., May, W.S., Jr., Le Vine, H., III, Cragoe, E.J., Jr., Cuatrecasas, P. 1985.J. Biol. Chem. 260:1155–1159

    Google Scholar 

  10. Bhalla, R.C., Sharma, R.V. 1986.J. Cardiovasc. Pharmacol. 8:927–932

    Google Scholar 

  11. Bielefeld, D.R., Hadley, R.W., Vassilev, P.M., Hume, J.R. 1986.Circ. Res. 59:381–389

    Google Scholar 

  12. Bierman, A.J., Tertoolen, L.G.J., Laat, S.W. de, Moolenaar, W.H. 1987.J. Biol. Chem. 262:9621–9628

    Google Scholar 

  13. Briggman, J.V., Graves, J.S., Spicer, S.S., Cragoe, E.J., Jr. 1983.Histochem. J. 15:239–255

    Google Scholar 

  14. Cassel, D., Cragoe, E.J., Jr., Rotman, M. 1987.J. Biol. Chem. 262:4587–4591

    Google Scholar 

  15. Cassel, D., Rotman, M., Cragoe, E.J., Jr., Igarashi, P. 1988.Anal. Biochem. 170:63–67

    Google Scholar 

  16. Cook, J.S., Shaffer, C., Cragoe, E.J., Jr. 1987.Am. J. Physiol. 253:C199-C204

    Google Scholar 

  17. Cornelisse, J., Havinga, E. 1975Chem. Rev. 75:353–388

    Google Scholar 

  18. Costa, C.J., Kirschner, L.B., Cragoe, E.J., Jr. 1984.J. Membrane Biol. 82:49–57

    Google Scholar 

  19. Cragoe, E.J., Jr. 1979.In: Amiloride and Epithelial Sodium Transport. A.W. Cuthbert, G.M. Fanelli, and A. Scriabine, editors. pp. 1–20. Urban & Schwarzenberg, Baltimore-Munich

    Google Scholar 

  20. Cragoe, E.J., Jr. 1983.In: Diuretics: Chemistry, Pharmacology, and Medicine E.J. Cragoe, Jr., editor. pp. 303–343. John Wiley & Sons, New York

    Google Scholar 

  21. Cragoe, E.J., Jr., Woltersdorf, O.W., Jr., Bicking, J.B., Kwong, S.F., Jones J.H. 1967.J. Med. Chem. 10:66–75

    Google Scholar 

  22. Cragoe, E.J., Jr., Woltersdorf, O.W., Jr., Solms, S.J. de 1981. U.S. Patent 4,246,406.

    Google Scholar 

  23. Cuthbert, A.W. 1976.Mol. Pharmacol. 12:945–957

    Google Scholar 

  24. Cuthbert, A.W., Edwardson, J.M. 1979.J. Pharm. Pharmacol. 31:382–386

    Google Scholar 

  25. Cuthbert, A.W., Edwardson, J.M. 1981.Biochem. Pharmacol. 30:1175–1183

    Google Scholar 

  26. Cuthbert, A.W., Fanelli, G.M. 1978.Br. J. Pharmacol. 63:139–149

    Google Scholar 

  27. Cuthbert, A.W., Shum, W.K. 1974.Naunyn-Schmiedeberg's Arch. Pharmacol. 281:261–269

    Google Scholar 

  28. Dannenbaum, D., Rosenheck, I. 1986.Biophys. J. 49:A370 (abstr.)

    Google Scholar 

  29. Davis, R.J., Czech, M.P. 1985.J. Biol. Chem. 260:2543–2551

    Google Scholar 

  30. Dixon, S.J., Cohen, S., Cragoe, E.J., Jr., Grinstein, S. 1986.J. Gen. Physiol. 88:19a (abstr.)

    Google Scholar 

  31. Dubinsky, W.P., Frizzell, R.A. 1983.Am. J. Physiol. 245:C157-C159

    Google Scholar 

  32. Friedrich, T., Sablotni, J., Burckhardt, G. 1986.J. Membrane Biol. 94:253–266

    Google Scholar 

  33. Garcia, M.L., King, V.F., Cragoe, E.J., Jr., Kaczorowski, G.J. 1987.Biophys. J. 51:428a (abstr.)

    Google Scholar 

  34. Garvin, J.L., Simon, S.A., Cragoe, E.J., Jr., Mandel, L.J. 1985.J. Membrane Biol. 87:45–54

    Google Scholar 

  35. Haggerty, J.G., Cragoe E.J., Jr., Slayman, C.W., Adelberg, E.A. 1985.Biochem. Biophys. Res. Commun. 127:759–767

    Google Scholar 

  36. Hamilton, K.L., Eaton, D.C. 1985.Am. J. Physiol. 245:C200-C207

    Google Scholar 

  37. Harris, R.C., Lufburrow, R.A., III, Cragoe, E.J., Jr., Seifter, J.L. 1985.Kidney Int. 27:310, (abstr.)

    Google Scholar 

  38. Howard, M.J., Mullen, M.D., Insel, P.A. 1987.Am. J. Physiol. 253:F21-F25

    Google Scholar 

  39. Ives, H.E., Yee, V.J., Warnock, D.G. 1983.J. Biol. Chem. 258:9710–9716

    Google Scholar 

  40. Johnson, J.D., Epel, D., Paul, M. 1976.Nature (London) 262:661–664

    Google Scholar 

  41. Kaczorowski, G.J., Barrows, G.J., Dethmers, J.K., Trumble, M.J. 1985.Biochemistry 24:1394–1403

    Google Scholar 

  42. Kim, B., Smith, T.W. 1986.Mol. Pharmacol. 30:164–170

    Google Scholar 

  43. Kinsella, J.L., Aronson, P.S. 1981.Am. J. Physiol. 241:F374-F379

    Google Scholar 

  44. Kleyman, T., Crudo, J., Cragoe, E., Jr., Al-Awqati, Q., Rossier, B., Kraehenbuhl, J.-P. 1987.Experientia 43:688 (abstr.)

    Google Scholar 

  45. Kleyman, T.R., Rajagopalan, R., Cragoe, E.J., Jr., Erlanger, B.F., Al-Awqati, Q. 1986.Am. J. Physiol. 250:C165-C170

    Google Scholar 

  46. Kleyman, T.R., Yulo, T.R., Ashbaugh, C., Landry, D., Cragoe, E., Jr., Karlin, A., Al-Awqati, Q. 1986.J. Biol. Chem. 261:2839–2943

    Google Scholar 

  47. Kleyman, T., Yulo, T., Cragoe, E.J., Jr., Al-Awqati, Q. 1986.Kidney Int. 29:400 (abstr.)

    Google Scholar 

  48. Koch, K.S., Leffert, H.L. 1979.Cell 18:153–163

    Google Scholar 

  49. Kuijpers, G.A.J., DePont, J., Nooy, E. van, Fleuren-Jakobs, A., Bonting, S., Rodrigues de Miranda, J. 1984.Biochim. Biophys. Acta 804:237–244

    Google Scholar 

  50. L'Allemain, G., Franchi, A., Cragoe, E., Jr., Pouyssegur, J. 1984.J. Biol. Chem. 259:4313–4319

    Google Scholar 

  51. LaBelle, E.F., Woodward, P.L., Cragoe, E.J., Jr. 1984.Biochim. Biophys. Acta 778:129–138

    Google Scholar 

  52. Langer, G.A. 1982.Annu. Rev. Physiol. 44:435–449

    Google Scholar 

  53. Lazorick, K., Miller, C., Sariban-Sohraby, S., Benos, D. 1985.J. Membrane Biol. 86:69–77

    Google Scholar 

  54. Leffert, H.L., Koch, K.S., Fehlmann, M., Heiser, W., Lad, P.J., Skelly, H. 1982.Biochem. Biophys. Res. Commun. 108:738–745

    Google Scholar 

  55. Li, J.H.-Y., Cragoe, E.J., Jr., Lindemann, B. 1985.J. Membrane Biol. 83:45–56

    Google Scholar 

  56. Li, J.H.-Y., Cragoe, E.J., Lindemann, B. 1987.J. Membrane Biol. 95:171–185

    Google Scholar 

  57. Lubin, M., Cahn, F., Coutermarsh, B.A. 1982.J. Cell. Physiol. 113:247–251

    Google Scholar 

  58. Mahe, Y., Garcia-Romeu, F., Montais, R. 1985.Eur. J. Pharmacol. 116:199–206

    Google Scholar 

  59. Margolius, H.S., Chao, J. 1980.J. Clin. Invest. 65:1343–1350

    Google Scholar 

  60. Meloche, S., Ong, H., De Lean, A. 1987.J. Biol. Chem. 262:10252–10258

    Google Scholar 

  61. Moolenaar, W.H., Tertoolen, L.G.V., Laat, S.W. de 1984.Nature (London) 312:371–374

    Google Scholar 

  62. O'Donnell, M.E., Cragoe, E., Jr., Villereal, M.L. 1983.J. Pharmacol. Exp. Ther. 226:368–372

    Google Scholar 

  63. Palaty, V. 1985.Can. J. Physiol. Pharmacol. 63:1586–1589

    Google Scholar 

  64. Palmer, L.G. 1984.J. Membrane Biol. 80:153–165

    Google Scholar 

  65. Palmer, L.G., Frindt, G. 1986.Proc. Natl. Acad. Sci. USA 83:2767–2770

    Google Scholar 

  66. Paris, S., Pouyssegur, J. 1984.J. Biol. Chem. 259:10989–10994

    Google Scholar 

  67. Pouyssegur, J., Chambard, J.C., Franchi, A., Paris, S., Obberghen-Schilling, E. van 1982.Proc. Natl. Acad. Sci. USA 79:3935–3939

    Google Scholar 

  68. Ralph, R.K., Smart, J., Wojcik, S.M., McQuillan, J. 1982.Biochem. Biophys. Res. Commun. 104:1054–1059

    Google Scholar 

  69. Renner, E.L., Lake, J.R., Cragoe, E.J., Jr., Scharschmidt, B.F. 1986.J. Cell Biol. 103:457a (abstr.)

    Google Scholar 

  70. Reuss, L., Petersen, K.U. 1985.J. Gen. Physiol. 85:409–429

    Google Scholar 

  71. Sariban-Sohraby, S., Benos, D.J. 1986.Biochemistry 25:4639–4646

    Google Scholar 

  72. Sariban-Sohraby, S., Benos, D.J. 1986.Am. J. Physiol. 250:C175-C190

    Google Scholar 

  73. Schellenberg, G.D., Anderson, L., Cragoe, E.J., Jr., Swanson P.D. 1985.Mol. Pharmacol. 27:537–543

    Google Scholar 

  74. Seifter, J.L., Aronson, P.S. 1986.J. Clin. Invest. 78:859–864

    Google Scholar 

  75. Simchowitz, L., Cragoe, E.J., Jr. 1986.Mol. Pharmacol. 30:112–120

    Google Scholar 

  76. Simchowitz, L., Woltersdorf, O.W., Jr., Cragoe, E.J., Jr. 1987.J. Biol. Chem. 262:15875–15975

    Google Scholar 

  77. Soltoff, S.P., Cragoe, E.J., Jr., Mandel, L.J. 1986.Am. J. Physiol. 250:C744-C749

    Google Scholar 

  78. Soltoff, S.P., Mandell, L.J. 1983.Science 220:957–958

    Google Scholar 

  79. Vassalli, J.-D., Belin, D. 1987.FEBS Lett. 214:187–191

    Google Scholar 

  80. Velly, J., Grima, M., Decker, N., Cragoe, E.J., Jr., Schwartz, J. 1988.Eur. J. Physiol. 149:97–105

    Google Scholar 

  81. Vigne, P., Frelin, C., Audinot, M., Borsotto, M., Cragoe, E.J., Jr., Lazdunski, M. 1984.EMBO J. 3:2647–2651

    Google Scholar 

  82. Vigne, P., Frelin, C., Cragoe, E.J., Jr., Lazdunski, M. 1984.Mol. Pharmacol. 25:131–136

    Google Scholar 

  83. Vigne, P., Frelin, C., Lazdunski, M. 1985.J. Biol. Chem. 260:8008–8013

    Google Scholar 

  84. Yang, W.C., Lowe, A., Warnock, D.G. 1987.Kidney Int. 31:443 (abstr.)

    Google Scholar 

  85. Warnock, D., Kleyman, T., Cragoe, E.J., Jr. 1988.FASEB J. 2:A753 (abstr.)

    Google Scholar 

  86. Zhuang, Y., Cragoe, E.J., Jr., Shaikewitz, T., Glaser, L., Cassel, D. 1984.Biochemistry 23:4481–4488

    Google Scholar 

Download references

Author information

Author notes

  1. Thomas R. Kleyman

    Present address: Renal and Electrolyte Section, Department of Medicine, University of Pennsylvania, 3400 Spruce Street, 19104, Philadelphia, PA

Affiliations

  1. Department of Medicine, Columbia University, 10032, New York, New York

    Thomas R. Kleyman & Edward J. Cragoe Jr.

  2. Merck Sharp and Dohme Research Laboratories, 19486, West Point, Pennsylvania

    Thomas R. Kleyman & Edward J. Cragoe Jr.

Authors
  1. Thomas R. Kleyman
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Edward J. Cragoe Jr.
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Kleyman, T.R., Cragoe, E.J. Amiloride and its analogs as tools in the study of ion transport. J. Membrain Biol. 105, 1–21 (1988). https://doi.org/10.1007/BF01871102

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01871102

Key Words

  • amiloride
  • amiloride analogs
  • ion transport
  • Na channel
  • Na/H exchanger
  • Na/Ca exchanger