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On the effects of amphotericin B and ouabain on the electrical potentials ofNecturus gallbladder

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Conclusion

The experimental evidence against an electrogenic pump in theNecturus gallbladder is nonexistent because they are based upon insufficient knowledge about the true resistance of the serosal membrane: The data available are not incompatible with the existence of an electrogenic pump with a coupling ratio of 3∶2-if an ionic model of the cell behavior is used.

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Authors and Affiliations

  1. The Panum Institute Institute of Medical Physiology, Dept. A, University of Copenhagen, DK-2200, Copenhagen, Denmark

    T. Zeuthen

  2. Department of General and Experimental Pathology, University of Vienna, Wahringerstrasse 13, A-1090, Vienna, Austria

    J. Graf

  3. Department of Physiology, Yale University School of Medicine, 333 Cedar Street, 06510, New Haven, CT

    S. A. Lewis & G. Giebisch

Authors
  1. T. Zeuthen
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  2. J. Graf
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  3. S. A. Lewis
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  4. G. Giebisch
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Zeuthen, T., Graf, J., Lewis, S.A. et al. On the effects of amphotericin B and ouabain on the electrical potentials ofNecturus gallbladder. J. Membrain Biol. 60, 167–170 (1981). https://doi.org/10.1007/BF01870419

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  • DOI: https://doi.org/10.1007/BF01870419

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