Summary
This paper describes a parameter free model of the electrostatic structure of gramicidin channels incorporated into uncharged lipid bilayer membranes. The electrical potential due to all sources is calculated for singly and doubly occupied channels. The model is consistent with all channel properties that are elearly dependent on coulombic interactions. The calculated value of the translocation rate constant and of the binding constant ratio for single and double occupancy are in excellent accord with experiment.
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Jordan, P.C. The total electrostatic potential in a gramicidin channel. J. Membrain Biol. 78, 91–102 (1984). https://doi.org/10.1007/BF01869197
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DOI: https://doi.org/10.1007/BF01869197