The Journal of Membrane Biology

, Volume 27, Issue 1, pp 393–408 | Cite as

On the mechanism of electrical coupling between cells of earlyXenopus embryos

  • R. A. DiCaprio
  • A. S. French
  • E. J. Sanders


The mechanism of electrical coupling between cells of earlyXenopus embryos has been studied by examination of the nonjunctional membrane resistances and capacitances as a function of cleavage stage, the junctional and nonjunctional membrane resistances as functions of time during the first cleavage, and the electrical properties of the primitive blastocoel. The changes in membrane resitances and capacitances during the first two cleavages may be completely explained by the addition of new membrane, identical in specific resistance and capacitance to the original membrane, at a constant rate to furrows which are electrically connected to the perivitelline space. Microelectrode recording from the primitive blastocoel indicates that there is no electrical difference detectable between it and the perivitelline space. These results are discussed in the context of current theories of the mechanism of intercellular electrotonic coupling.


Human Physiology Electrical Property Current Theory Membrane Resistance Cleavage Stage 
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Copyright information

© Springer-Verlag New York Inc. 1976

Authors and Affiliations

  • R. A. DiCaprio
    • 1
  • A. S. French
    • 1
  • E. J. Sanders
    • 1
  1. 1.Department of PhysiologyUniversity of AlbertaEdmontonCanada

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