Skip to main content
SpringerLink
Log in

Die Hirnischämie als Ursache für die Änderung der Transplantationsantigene des Hundes im zytotoxischen Test

Alteration in the serological detection of transplantation antigens of the dog due brain ischemia and anesthesia

  • Published:
Research in Experimental Medicine

Summary

Experiments were performed on 19 mongrel dogs. Changes of transplantation antigens by anesthesia and by brain ischemia were identified in cytotoxic tests. Brain ischemia was responsible for the significant alteration in 5 antigens, anesthesia alone induced no significant changes.

Zusammenfassung

Von 19 Bastardhunden wurden unter den Versuchsbedingungen der Narkose und Hirnischämie die Transplantationsantigene im zytotoxischen Test bestimmt und ihre Veränderungen gegenüber dem Ausgangswert statistisch erfaßt. Fünf Antigene änderten sich signifikant im Stadium der Hirnischämie. Mit den bisher erfolgten Mitteilungen über Änderungen bei Histokompatibilitätsantigenen wird eine Deutung der geschilderten Befunde versucht.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literatur

  1. BHANDARI, S.C., SINGAL, D.P.: Tissue Antigens3 140 (1973)

    PubMed  Google Scholar 

  2. BUBE, F.W., SIEBEL, E., HEUMANN, H.: Vox Sang.25 327 (1973)

    PubMed  Google Scholar 

  3. DICK, H.M., BRIGGS, J.D., WOOD, R.F.M., BELL, P.R.F.: Tissue Antigens2 345 (1972)

    PubMed  Google Scholar 

  4. Eurotransplant Foundation, Leiden, Mitteilung vom 15. 2. 1972

  5. FISCHER, J.H., SCHILDBERG, F.W., ISSELHARD, W.: Pflügers Arch.335 335 (1972)

    Google Scholar 

  6. GIBOFSKY, A., TERASAKI, P.I.: Transplantation13 192 (1972)

    PubMed  Google Scholar 

  7. GOODMAN, L.A., KRUSKAL, W.H.: J. Amer. stat. Ass.49 732 (1954)

    Google Scholar 

  8. GOODMAN, L.A., KRUSKAL, W.H.: J. Amer. stat. Ass.49 310 (1963)

    Google Scholar 

  9. KEDAR, E., BONAVIDA, B.: J. of Immunol.113 1544 (1974)

    Google Scholar 

  10. LUNDGREN, G., MAGNUSSON, G., MÜLLER, E., NORDENSTAM, H., WERNER, B., WESTBERG, G.: Tissue Antigens2 32, (1972)

    PubMed  Google Scholar 

  11. MAJSKY, A.: Folia haemat. (Lpz.)101 608 (1974)

    Google Scholar 

  12. Manual of Techniques used in the first International Workshop on Canine Immunogenetics at the Medical Faculty of the Erasmus University Rotterdam, p.5 (1972)

  13. MITTAL, K.K., MICKEY, M.R., SINGAL, D.P., TERASKI, P.I.: Transplantation6 913 (1968)

    PubMed  Google Scholar 

  14. MOTTA, R., BRULEY, M.: Transplantation15 22 (1973)

    PubMed  Google Scholar 

  15. OHAYON, E., DUCOS, J., GORET, P., SALMON, H., TORNE, B.: Lancet7740 39 (1972)

    Google Scholar 

  16. OPELZ, G., MICKEY, M.R., TERASAKI, P.I.: Transplantation17 371 (1974)

    PubMed  Google Scholar 

  17. PEGRUM, G.D., BALFOUR, I.C., EVANS, C.A., MIDDELTON, V.L.: Lancet7704 852 (1971)

    Google Scholar 

  18. RAY, P.K., GEWURZ, H., SIMMONS, R.L.: Clin. exp. Immunol.11 441 (1972)

    PubMed  Google Scholar 

  19. RUDDY, S.: Transplant. Proc.6 1 (1974)

    Google Scholar 

  20. TERASAKI, P.I., MC CELLAND, J.D.: Nature204 998 (1964)

    Google Scholar 

  21. TING, A., TERASAKI, P.I.: Transplantation18 371 (1974)

    PubMed  Google Scholar 

  22. TURNIPSEED, W.P., FOLGER, M.R., CERILLI, J.: Transplantation17 341 (1974)

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Abt. f. Transfusionswesen, d. Univ.-Kliniken Köln, Josef-Stelzmann-Str. 9, D-5000, Köln 41, Bundesrepublik Deutschland

    E. Siebel, E. Geppert, H. Heumann, W. Haase, W. Stock, J. Sturz, F. W. Bube & W. Isselhard

  2. Institut für Experimentelle Medizin, Josef-Stelzmann-Str. 9, D-5000, Köln 41, Bundesrepublik Deutschland

    E. Siebel, E. Geppert, H. Heumann, W. Haase, W. Stock, J. Sturz, F. W. Bube & W. Isselhard

Authors
  1. E. Siebel
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. E. Geppert
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. H. Heumann
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. W. Haase
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. W. Stock
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. J. Sturz
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. F. W. Bube
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. W. Isselhard
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Siebel, E., Geppert, E., Heumann, H. et al. Die Hirnischämie als Ursache für die Änderung der Transplantationsantigene des Hundes im zytotoxischen Test. Res. Exp. Med. 166, 229–233 (1975). https://doi.org/10.1007/BF01852635

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01852635

Key words

Schlüsselwörter

Search

Navigation