Summary
The influence of an additional fiber diet on biliary lipid composition of gallbladder bile was studied in 12 piglets. In addition to the standard feed wheat bran was given for 6 weeks and bassorin for 2 weeks to each of four piglets. A group of four piglets served as controls. Gallbladder bile was obtained by ultrasonically guided puncture of the gallbladder. The results showed no significant alteration of bile acids, lipid composition, and lithogenity of bile for either of the diets. These findings are interpreted in that way that the normally high basic fiber content of the food of piglets does not allow a further decrease of the lithogenic index by addition of wheat bran or bassorin. This conclusion would mean that the basic fiber diet should be known before therapeutic trials with fiber diets are planned or interpreted.
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References
Goebell H (1977) Die Epidemiologie des Gallensteinleidens. Akt Ernährung 3:95–102
Harvey RF, Pomare EW, Heaton KW (1973) Effects of increased dietary fiber on intestinal transit. Lancet 1:1278–1280
Haslewood GAD (1964) The biological significance of chemical differences in bile salts. Biol Rev 39:537–574
Haslewood GAD (1967) Bile salt evolution. J Lipid Res 8:535–550
Klapdor R (1977) The ultrasonically guided puncture of the gallbladder in animals. Endoscopy 9:166–169
Klapdor R (1977) Effects of fasting on biliary lipid composition in the pig. Hell Med Soc [Suppl] 3:49
Low-Beer TS, Pomare EW, Morris JS (1972) Control of bile salt synthesis. Nature 238:215
Low-Beer TS, Pomare EW (1973) The human bile salt feed back and its specifity. Gastroenterology 64:764
Matzkies F (1981) Wirkung des inerten Quellstoffs Bassorin auf die Stuhlproduktion, den Mineralhaushalt und den Stoffwechsel. Klinikarzt 1:74–78
Payler DK, Pomare EW, Heaton KW, Harvey RF (1975) The effect of wheat bran on intestinal transit. GUT 16:208–213
Pomare EW, Heaton KW (1973) Alteration of the bile salt metabolism by dietary fiber (bran). Br Med J 4:262–264
Pomare EW, Heaton KW, Low-Beer TS, Espiner HJ (1976) The effect of wheat bran upon bile salt metabolism and upon lipid composition of bile in gallstone patients. Dig Dis 21:521–526
Splitter GA (1972) Cholelithiasis in a pig. Vet Rec 90:73
Thomas PJ, Hofmann AF (1973) A simple calculation of the lithogenic index of bile. Gastroenterology 4:698–700
Wicks ACB, Yeates J, Heaton KW (1978) Brain and bile: Time-course of changes in normal young man given a standard dose. Scand J Gastroenterol 13:289–292
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Klapdor, R., Hein, C. Addition of fiber (wheat bran, bassorin) to the standard food does not influence biliary lipid composition in piglets. Res. Exp. Med. 180, 21–24 (1982). https://doi.org/10.1007/BF01852228
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DOI: https://doi.org/10.1007/BF01852228