Skip to main content
Log in

Tierexperimentelle Untersuchungen der Magendurchblutung

I. Normaldurchblutung

Gastric blood flow in animals

I. Normal Blood Flow

  • Original Works / Originalarbeiten
  • Published:
Research in Experimental Medicine

Summary

Total and regional gastric blood flow were measured in 15 dogs under control conditions (mean AOBP 100 mm Hg) using microspheres labelled with different isotopes (125J,141Ce,85Str,46Sc) of 8 µ size.

The mucosa in fundus and corpus showed significantly higher blood flow compared to the antrum. There was no difference in the muscular layer for either part of the stomach. It is concluded from these data that differences in regional blood flow in the unstimulated stomach of the dog are related to different energy-demands within the stomach.

Zusammenfassung

Bei 15 Hunden werden unter Kontrollbedingungen (mittlerer Aortendruck 100 mm Hg) der totale und regionale Blutfluß des Magens mit der Microspheres-Methode gemessen. Die Verwendung von 8 µ großen, radioaktiv markierten Microspheres (125J,141Ce,85Str,46Sc) macht die quantitative Bestimmung der Durchblutung kleinster Areale des Magens möglich.

Es werden signifikant unterschiedliche Flußgrößen der Magenschleimhaut in den einzelnen Arealen ermittelt. Die Durchblutung der Fundus- und Corpusschleimhaut liegt höher als die des Antrum. Die Muskularis wird in allen Magenanteilen gleich gut durchblutet. Differenzen regionaler Durchblutungsgrößen am nichtstimulierten Magen machen energetisch unterschiedliche Bedarfssituationen verschiedener Magenareale wahrscheinlich.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literatur

  1. Archibald, L. H., Moody, Simons, M.: Measurements of gastric blood flow with radioactive microspheres. J. Appl. Physiol.38, 1051 (1975)

    PubMed  Google Scholar 

  2. Buckberg, G. D., Luck, J. C., Payne, D. B., Hoffmann, J. L.: Some sources of error in measuring regional blood flow with radioactive microspheres. J. Appl. Physiol.31, 598 (1971)

    PubMed  Google Scholar 

  3. Burton-Opitz, R.: Über die Strömung des Blutes in dem Gebiete der Pfortader. Pflüger's Arch. Ges. Physiol.135, 205 (1971)

    Google Scholar 

  4. Cummings, J. D., Haigh, A. L., Harries, E. H. L., Nutt, M. E.: A study of gastric secretion and blood flow in the anaesthesized dog. J. Physiol.168, 219 (1963)

    PubMed  Google Scholar 

  5. Delaney, J. P., Grim, E.: Experimentally induced variations in canine gastric blood flow and its distribution. Am. J. Physiol.208, 3532 (1965)

    Google Scholar 

  6. Demling, L., Ottenjann, R., Wachsmann, F.: Method for measurement of blood flow and acidity in the human stomach. Am. J. Dig. Dis., N.S.9, 517 (1969)

    Google Scholar 

  7. Hottenrott, Ch., Seufert, R. M., Becker, H., Encke, A.: Der Einfluß von Vagus und Sympathicus auf die Durchblutung des Ferkelmagens. Langenbecks Arch. Suppl. Chir. Forum, p. 224, 1976

  8. Jacobsen, E. D.: Clearance of the gastric mucosa. Gastroenterology54, 434 (1968)

    PubMed  Google Scholar 

  9. Menguy, R., Masters, Y. F.: Gastric mucosal energy metablolism and Stress ulceration. Ann. Surg.180, 249 (1979)

    Google Scholar 

  10. Neutze, J. M., Whyler, F., Rudolph, A. M.: Use of radioactive microspheres to assess distribution of cardiac output in rabbits. Am. J. Physiol.215, 486 (1968)

    PubMed  Google Scholar 

  11. Rudolph, A. M., Heyman, R. A.: Circulation of the fetus in utero: Methods for studying distribution of blood flow, cardiac output and organ blood flow. Circ. Res.12, 163 (1967)

    Google Scholar 

  12. Salmon, P. A., Griffin, W. O. jr., Wangensteen, O. H.: Effect of intragastric temperature changes upon gastric blood flow. Proc. Soc. Exp. Biol. Med.101, 442 (1959)

    PubMed  Google Scholar 

  13. Wagner, H. N., Rhodes, B. A., Sasaki, Y., Ryan, J. P.: Studies of the circulation with radioactive microspheres. Invest. Radiol.4, 374 (1969)

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Mit Unterstützung der Deutschen Forschungsgemeinschaft

Rights and permissions

Reprints and permissions

About this article

Cite this article

Becker, H., Hottenrott, C., Seufert, R.M. et al. Tierexperimentelle Untersuchungen der Magendurchblutung. Res. Exp. Med. 176, 31–36 (1979). https://doi.org/10.1007/BF01852109

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01852109

Key words

Schlüsselwörter

Navigation