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Unresponsiveness of exocrine rat pancreas to calcemic challenges (hypercalcemia, EDTA hypocalcemia or calcitonin administration) which influence stomach function

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Research in Experimental Medicine

Summary

In the rat, stimulated exocrine pancreatic secretion is not influenced by acute hypercalcemia, EDTA hypocalcemia or calcitonin administration. This unresponsiveness is in contrast to the reaction of the rat stomach to calcemic challenges.

Zusammenfassung

Die stimulierte exokrine Pankreasfunktion der Ratte läßt sich durch akute Hypercalciämie, ÄDTA-Hypocalciämie oder Calcitoningabe nicht beeinflussen. Dieses Verhalten steht im Gegensatz zur Reaktion des Magens der Ratte auf Calciumreize.

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Abbreviations

BTEE:

benzoyl-tyrosine-ethyl-ester

EDTA:

ethylene-diaminetetra-acetate

MRCmU:

Medical Research Council milliunits

TAME:

toluolearginine-methyl-ester

References

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Authors and Affiliations

  1. Department of Internal Medicine, Endocrinology and Metabolism and Section of Gastroenterology, Center of Internal Medicine and Pediatrics, University of Ulm, Steinhövelstraße 9, D-7900, Ulm, Federal Republic of Germany

    R. Ziegler, H. Minne, M. Zwicker & J. Hotz

Authors
  1. R. Ziegler
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  2. H. Minne
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  3. M. Zwicker
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  4. J. Hotz
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Supported by “Deutsche Forschungsgemeinschaft”, Bad Godesberg.

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Ziegler, R., Minne, H., Zwicker, M. et al. Unresponsiveness of exocrine rat pancreas to calcemic challenges (hypercalcemia, EDTA hypocalcemia or calcitonin administration) which influence stomach function. Res. Exp. Med. 162, 347–350 (1974). https://doi.org/10.1007/BF01851706

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  • DOI: https://doi.org/10.1007/BF01851706

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