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Zur Frage der Umwandlung haematogener Monozyten zu Fibroblasten in heilenden Wunden

Transformation of monocytes into fibroblasts in wound healing

  • Published:
Research in Experimental Medicine

Summary

Recent investigations of HELPAP and CREMER 1972 seem to confirm the supposition of COHNHE IM 1867 that monocytes of the peripheral blood are transformed into firbroblasts in healing wounds.

The view of VIRCHOW 1871, MARCHAND 1901 and ASCHOFF 1924 that the fibroblasts in healing wounds are of local origin seems to be supported by the investigation on parabiotic inbred rats of ROSSet al. 1970.

We thought that irradiating the whole body of rabbits could be of value in resolving these apparent contradictions about the origin of fibroblasts in healing wounds.

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    S. Krupp

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Krupp, S. Zur Frage der Umwandlung haematogener Monozyten zu Fibroblasten in heilenden Wunden. Res. Exp. Med. 167, 85–126 (1976). https://doi.org/10.1007/BF01851593

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