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Plasma protein response in experimental inflammation in the dog

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Research in Experimental Medicine

Summary

The changes in plasma protein concentration in experimental inflammation in dogs were studied. Arthritis, turpentine injury, thrombophlebitis, proctitis and cholecystectomy were produced in the animals. The orosomucoid concentration rose to values higher than those seen in man. C-reactive protein, fibrinogen, haptoglobin, ceruloplasmin andβ 1 c-globulin increased in concentration in the same way as in man. In contrast with what is seen in human beings,α 1-antitrypsin did not increase andα 2-macroglobulin was clearly reduced during the inflammation.

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Authors and Affiliations

  1. Department of Clinical Chemistry, University of Lund, Malmö General Hospital, S-214 01, Malmö, Sweden

    K. Ganrot

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  1. K. Ganrot
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Additional information

This investigation was supported by grants from the Swedish Medical Research Council (Project No. B72-13 X-581-08 A).

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Ganrot, K. Plasma protein response in experimental inflammation in the dog. Res. Exp. Med. 161, 251–261 (1973). https://doi.org/10.1007/BF01851449

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  • DOI: https://doi.org/10.1007/BF01851449

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