Summary
Isoproterenol-activation of the adenylate cyclase system of human fat cell ghosts was markedly inhibited by dihydroergotamine which had no effect on basal and NaF-stimulated enzyme activity. Our results indicate that the antilipolytic action of this substance in human adipose tissue is probably due to inhibition of catecholamine-sensitive adenylate cyclase activity.
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Kather, H., Vogt, B. & Simon, B. Catecholamine-sensitive adenylate cyclase of human fat cell ghosts. Res. Exp. Med. 170, 253–257 (1977). https://doi.org/10.1007/BF01851435
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DOI: https://doi.org/10.1007/BF01851435