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Research in Experimental Medicine

, Volume 181, Issue 3, pp 205–210 | Cite as

Effekt von Calcium und Magnesium auf die Parathormonfreisetzung aus humanem Parathyreoidea-Gewebe in vitro

  • P. K. Wagner
  • U. Krause
  • M. Rothmund
Original Contributions

Effect of calcium and magnesium on parathyroid hormone release from human adenomatous and secondary hyperplastic parathyroid tissue in vitro

Summary

The effects of calcium and magnesium on parathyroid hormone release from eight adenomas causing primary hyperparathyroidism and six hyperplastic glands causing hypercalcemic secondary hyperparathyroidism were investigated in vitro using single cell suspensions from the respective tissue. We observed suppression of parathyroid hormone release with increasing concentrations of either cation. The quantitative hormone secretions of both adenomatous and hyperplastic glands was identical.

Key words

Hyperparathyroidism Cell suspension Calcium Magnesium 

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Copyright information

© Springer-Verlag 1982

Authors and Affiliations

  • P. K. Wagner
    • 1
  • U. Krause
    • 2
  • M. Rothmund
    • 1
  1. 1.Chirurgische KlinikII. Medizinische Klinik der Johannes-Gutenberg-UniversitätMainzBundesrepublik Deutschland
  2. 2.Endokrinologische AbteilungII. Medizinische Klinik der Johannes-Gutenberg-UniversitätMainzBundesrepublik Deutschland

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