Advances in Contraception

, Volume 6, Issue 1, pp 23–32 | Cite as

A three-year evaluation of hemostatic function in Singaporean Norplant acceptors

  • K. Singh
  • O. A. C. Viegas
  • S. S. Ratnam
Article

Abstract

In a longitudinal study involving 100 Singaporean women, results indicate that the acceptors persist in having a possibly increased predisposition to thrombosis, as evidenced by a significant increase in platelet count and aggregability. Furthermore, the shortened prothrombin time and activated partial thromboplastin time, together with changes in vitamin K factors, still indicate the possible enhanced potential for hypercoagulation.

Keywords

Public Health Vitamine Longitudinal Study Platelet Count Prothrombin 

Resumé

Dans l'étude longitudinale effectuée sur 100 femmes singapouriennes, les résultats indiquent que celles-ci ont continué à présenter ce qui est peut-être une prédisposition accrue à la thrombose, ainsi que l'a fait ressortir l'augmentation significative du nombre de plaquettes et de leur possibilité d'agrégation. En outre, le raccourcissement du temps de prothrombine et l'accélération du temps de thromboplastine partielle associés aux changements des facteurs de la vitamine K indiquent encore la possibilité d'une élévation potentielle de l'hypercoagulation.

Resumen

En el estudio longitudinal efectuado con 100 mujeres de Singapur, los resultados indican que continúan presentando lo que puede ser una predisposición acrecentada a la trombosis, según lo señalado por un aumento significativo del número de plaquetas y su posible agregación. Por otra parte, el acortamiento del tiempo de protrombina y la aceleración del tiempo de tromboplastina parcial asociados con los cambios de los factores de la vitamina K continúan indicando la posibilidad de un aumento potencial de la hipercoagulación.

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Copyright information

© Kluwer Academic Publishers 1990

Authors and Affiliations

  • K. Singh
    • 1
  • O. A. C. Viegas
    • 1
  • S. S. Ratnam
    • 1
  1. 1.Department of Obstetrics and GynaecologyNational University HospitalSingapore

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