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Sequential hormone measurements after first trimester abortion in normal Nigerian women

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Advances in Contraception

Abstract

This study looks at the dynamics of the pituitary hormones and progesterone in normal adult Nigerian females during their first postabortal cycle. Serial determinations of serum concentrations of luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (PrL) and progesterone were carried out on eleven normal Nigerian women during the first postabortal period after menstrual regulation. Nine out of the eleven subjects (82%) attained LH peaks within the first 22 days after menstrual regulation, seven had discernible FSH peaks and seven had serum progesterone concentrations greater than 6 nmol/l during the second half of the study period. Subjects probably ovulated during the first postabortal cycle; serial LH seems to be the most reliable index of ovulation in our subjects. We hope these data will aid in development of effective family planning strategies for women in the first postabortal cycle.

Resumé

Cette étude concerne la dynamique des hormones hypophysaires et de la progestérone chez des femmes Nigériennes adultes, normales, pendant le premier cycle suivant un avortement. On a pratiqué des dosages successifs des taux sériques de LH, de FSH, de prolactine et de progestérone chez 11 femmes Nigériennes normales pendant le premier cycle post-abortif après les règles. Chez 9 des 11 femmes (82%) le pic de LH a été atteint au cours des 22 premiers jours suivant les règles; chez 7 on a trouvé des pics décelables de FSH et chez 7 des taux sériques de progestérone supérieurs à 6 nmol/l pendant la seconde moitié de la période d'étude. Ces femmes ont sans doute ovulé pendant le premier cycle post-abortif. Chez nos patientes, les mesures successives du taux de LH paraissent constituer l'index le plus fiable de l'ovulation. Nous espérons que nos résultats faciliteront la mise au point de stratégies efficaces de planning familial chez les femmes, au cours du premier cycle post-abortif.

Resumen

Este estudio observa la dinámica de las hormonas de la pituitaria y la progesterona en mujeres adultas normales nigerianas, durante el primer ciclo post-aborto. Determinaciones seriades en suero de hormona luteinizante (LH), de hormona folículo astimulate (FSH), prolactina y progesterona, fueron hechas en once mujeres normales durante el primer período post-aborio después de la regulación menstrual. Nueve (82%) de once sujetos alcanzaron el máximo de LH durante los primeros 22 días después de la regulación menstrual, siete tuvieron máximas de FSH y siete tuvieron concentraciones de progesterona en suero mayores de 6 nmol/l durante la segunda mitad del período en estudio. La mayoría de las mujeres probablemente ovularon durante el primer ciclo post-aborto y la determinación repetida de LH es el índice más confiable de ovulación en nuestros sujetos. Esperamos que estos datos contribuyan al desarrollo de estrategias efectivas en la planificación familiar para mujeres en al primer ciclo post-aborto.

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Osotimehin, B., Otolorin, E.O. & Ladipo, O.A. Sequential hormone measurements after first trimester abortion in normal Nigerian women. Adv Contracept 1, 83–90 (1985). https://doi.org/10.1007/BF01849147

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  • DOI: https://doi.org/10.1007/BF01849147

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