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Linkage between low-density lipoprotein and igk light-chain genes in rabbits

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Abstract

The rabbit geneLpq, which codes for a low-density serum lipoprotein2, is linked (34.6 ± 5.3 centimorgans) to the Ig kappa light-chain gene (Ab). There is no evidence thatLpq is linked to another gene,Prt, that was previously found to be linked to theAb gene. This suggests that the gene order for the three genes isPrt- Ab- Lpq.

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Abbreviations

Ig:

immunoglobulin

a :

the heavy-chain variable-region geneAa

b :

the kappa light-chain geneAb

q :

the low-density serum lipoprotein geneLpq

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Usher, D.C., Mayer, E.P., Dray, S. et al. Linkage between low-density lipoprotein and igk light-chain genes in rabbits. Immunogenetics 7, 117–123 (1978). https://doi.org/10.1007/BF01843996

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