Abstract
Two B-lymphocyte-specific human alloantisera were studied, PA59 and 51.23. They identify two new HLA-DR alleles, which are both subtypic to HLA-DRw2. Moreover, they are closely correlated with two HLA-D products, Dw2 and tb24 (tb24 is a new specificity described by our group). Thus, DRw2 can be “split” into two subtypic specificities that have been named TO60 and TO61, which appear more strongly correlated with HLA-D antigens. Absorption studies demonstrated cytotoxicity-negative, absorption-positive (CYNAP) reactions, and cross-reactive groups of antibodies.
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Richiardi, P., Belvedere, M., Borelli, I. et al. Split of HLA-DRw2 into subtypic specificities closely correlated to two HLA-D products. Immunogenetics 7, 57–61 (1978). https://doi.org/10.1007/BF01843988
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DOI: https://doi.org/10.1007/BF01843988