Abstract
Murine T lymphocytes incubated in a mixed lymphocyte culture with allogeneic lymphocytes incompatible for theH-2 region or subregions thereof rapidly develop insulin receptors. In contrast, T cells cultured with syngeneic orH-2- andMlslocus compatible cells do not develop insulin-binding sites. The emergence of insulin receptors is probably an early premitotic event.
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Strom, T.B., Helderman, J.H. & Williams, R.M. Rapid murine mixed lymphocyte cultures assessed by emergence of T-cell insulin receptors. Immunogenetics 7, 51–56 (1978). https://doi.org/10.1007/BF01843987
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DOI: https://doi.org/10.1007/BF01843987