Prediction of the interaction effects Ar+ laser-brain tumours by study of the photoacoustic spectroscopy of cerebral oncotypes
- 19 Downloads
A preliminary definition of light absorption spectra of brain neoplasm represents a correct approach to the laser therapy of cerebral tumours. The goal should be the identification of those oncotypes more sensive to the laser energy, allowing consequentely a dosage of the energy proportional to the light absorption coefficient, reducing any side effects.
With this purpose the coefficients of light — absorption of 63 different brain tumours have been analyzed and defined by means of photocoustic spectrometry. The study has been focused at wave-length of the Ar+ laser (4,600–6,000 å).
The results show a close relationship between histology, degree of vascularization and/or pigmentation and light absorption: the more immature and/or pigmented oncotypes show the higest coefficients of optical absorption. In the laser therapy of these neoplasms it will be sufficient to use low powers and short exposure time.
KeywordsLaser surgery Ar+ laser photo-acoustic spectrometry cerebral tumour
Unable to display preview. Download preview PDF.
- 1.Boggan JE, Edwards MSB, Davis RL, Bolger CA, Martin N (1982) Comparison of the Brain tissue response in rats to injury by argon and carbon dioxide laser. Neurosurgery 5: 609–615Google Scholar
- 2.De Tommasi A, Occhiogrosso M, Vailati G, Baldassarre L, Cingolani A (1986) Evaluation of the Ar+ laser thermal effect in rabbit brain tissue by means of optical absorption coefficients. Photoacoustic measurements. Acta Neurochir (Wien) 79: 139–144Google Scholar
- 3.Hara M, Takeuchi K, Okada J (1980) Evaluation of brain tumor laser surgery. Acta Neurochir (Wien) 53: 241–249Google Scholar
- 6.Rosencwaig A (1978) Photoacoustic spectroscopy. In: Advances in electronics and electron physics. Academic Press, New YorkGoogle Scholar
- 7.Rosencwaig A, Gersho A (1976) Theory of the photoacoustic effects with solids. J Appl Phys 47: 64–70Google Scholar
- 9.Wetsel GC, McDonald FA (1977) Photoacoustic determination of absolute optical absorption coefficient. Appl Phys Lett 5: 252–254Google Scholar