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A study on the critical mobilization length of peripheral nerves

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Summary

The transverse section of the sciatic, tibial and peroneal nerves in rabbits was followed by mobilization in a proximal and distal direction and a tensionfree end-to-end suture of the cut surfaces. The proximal mobilization was performed up to eight different levels between 60 mm and 200 mm, i. e. 20.3% to 67.7% of the total nerve length. Histological findings and their statistical analysis indicated that the critical mobilization length, beyond which ischaemic parenchymal damages occur, is 70 mm or 24% of the total nerve length. Up to this level, the vascular ”extrinsic system“ of the mobilized nerve segments is completely compensated for by the ”intrinsic system“. When the mobilization length is increased, the degeneration distances were more pronounced than those of the ischaemic nerve distances. Some nerves showed no effects from the ischaemia.

Zusammenfassung

An den Nn. ischiadici, tibiales und peronaei von Kaninchen wurden nach transversaler Durchtrennung proximo-distale Mobilisationen vorgenommen und anschließend die freien Stümpfe spannungslos End-zu-End genäht. Die ascendierende Mobilisation erfolgte in 8 verschiedenen Dimensionen zwischen 60 mm und 220 mm, das sind 20,3% bis 67,7% der Nervengesamtlänge. Die kritische Mobilisationslänge eines Nerven, oberhalb welcher ischämische Parenchymschäden auftreten, wurde nach den histologischen Befunden und deren statistischer Auswertung bei 70 mm, entsprechend 24% der Nervengesamtlänge, gefunden. Bis dahin wiesen die mobilisierten Nervensegmente eine vollständige Kompensation der ausgeschalteten äußeren Blutzuflüsse durch das innere Gefäßsystem auf. Mit zunehmender Mobilisationslänge stiegen die Degenerationsstrekken stärker als die ischämischen Nervenstrecken an. Einzelne Nerven blieben ohne Ischämieeffekte.

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Orf, G., Schultheiss, R. A study on the critical mobilization length of peripheral nerves. Neurosurg. Rev. 4, 83–94 (1981). https://doi.org/10.1007/BF01837751

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