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Detection of brain tumours in patients with focal epilepsy by regional cerebral blood flow measurements

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Summary

Conventional neuroradiological procedures, including CT-scanning sometimes fail to reveal any cerebral lesion in patients with focal cortical epilepsy. Neuronal activity in a chronic epileptogenic focus is increased, even outside periods of seizures. The interictal neuronal hyperactivity, which does not necessarily give rise to spikes in the electroencephalogram, can sometimes be seen as an area of focal hyperaemia in the rCBF.

Zusammenfassung

Konventionelle neuroradiologische Methoden mit Einschluß der Computer-Tomographie zeigen manchmal einen hirnpathologischen Herd bei Patienten mit fokaler kortikaler Epilepsie nicht an. Dabei ist die neuronale Aktivität in einem chronischen epileptogenen Fokus verstärkt auch außerhalb der Perioden der Anfälle; während in der Zeit zwischen den Anfällen neuronale Hyperaktivität nicht unbedingt spikes im Elektroencephalogramm geben muß, kann sie doch gelegentlich als ein Bezirk mit fokaler Hyperämie im rCBF aufgedeckt werden.

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Authors and Affiliations

  1. Department of Neurosurgery, University Hospital, 59 Oostersingel, Groningen, The Netherlands

    H. J. Gelmers & C. A. ter Weeme

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  1. H. J. Gelmers
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  2. C. A. ter Weeme
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Gelmers, H.J., ter Weeme, C.A. Detection of brain tumours in patients with focal epilepsy by regional cerebral blood flow measurements. Neurosurg. Rev. 4, 79–82 (1981). https://doi.org/10.1007/BF01837750

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