, Volume 79, Issue 3, pp 185–188 | Cite as

Serologic grouping and sexual compatibility of airbornecryptococcus neoformans

  • S. C. Jong
  • G. S. Buhner
  • A. Ruiz


Through the use of Anderson air samplers, 214 isolates ofCryptococcus neoformans were cultured from the air in a vacant tower in a large complex of buildings in Oklahoma City. The tower contained hundreds of pigeons, a massive amount of droppings, nests with eggs and young, dying and dead pigeons. All isolates were serotype A-D and self-sterile for the production of basidiospores. Among these, 193 were of the ‘alpha’ mating type, producing basidiospores when paired with ‘a’ mating type. No isolates of ‘α’ mating type were found. The remaining 21 isolates were untypable for their mating type. These findings imply that the infectious particles ofC. neoformans in nature are relatively small, nonencapsulated yeast cells andnot basidiospores.


Mating Type Cryptococcus Neoformans Cryptococcosis Oklahoma City Mating Ability 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Bennett, J. E., Kwon-Chung, K. J. & Howard, D. H., 1977. Epidemiologic differences among serotypes of Cryptococcus neoformans. Am. J. Epidemiol. 105: 582–586.PubMedGoogle Scholar
  2. 2.
    Bennett, J. E., Kown-Chung, K. J. & Theodore, T. S., 1978. Biochemical differences between serotypes of Cryptococcus neoformans. Sabouraudia 16: 167–174.PubMedGoogle Scholar
  3. 3.
    Bowman, P. I. & Ahearn, D. G., 1978. Ecology of Cryptococcus neoformans in Georgia, pp. 258–268. In: Proceedings of the IV International Conference on the Mycoses. PAHO Scientific Publication No. 356. Pan Am. Health Org., Washington, D.C.Google Scholar
  4. 4.
    Denton, J. F. & DiSalvo, A. F., 1968. The prevalence of Cryptococcus neoformans in various natural habitats. Sabouraudia 6: 213–217.PubMedGoogle Scholar
  5. 5.
    Felton, F. G., Muchmore, H. G. & McCarty, M. A., 1974. Epidemiology of cryptococcosis: I. Environmental distribution of cryptococci in Oklahoma. Health Lab. Sci. 11: 201–204.PubMedGoogle Scholar
  6. 6.
    Kwon-Chung, K. J., 1975. A new genus, Filobasidiella the perfect state of Cryptococcus neoformans. Mycologia 67: 1197–1200.PubMedCrossRefGoogle Scholar
  7. 7.
    Kwon-Chung, K. J., 1976. Morphogenesis of Filobasidiella neoformans the sexual state of Cryptococcus neoformans. Mycologia 68: 821–833.PubMedCrossRefGoogle Scholar
  8. 8.
    Kwon-Chung, K. J., 1978. Heterothallism vs. self-fertile isolates of Filobasidiella neoformans (Cryptococcus neoformans). pp. 204-213. In: Proceedings of the IV International Conference on the Mycoses. PAHO Scientific Publication No. 356Google Scholar
  9. 9.
    Kwon-Chung, K. J., 1980. Nuclear genotypes of spores chains in Filobasidiella neoformans (Cryptococcus neoformans). Mycologia 72: 418–422.PubMedCrossRefGoogle Scholar
  10. 10.
    Kwon-Chung, K. J. & Bennett, J., 1978. Distribution of alpha and α mating types of Cryptococcus neoformans among natural and clinical isolates. Am. J. Epidemiol. 108: 337–340.PubMedGoogle Scholar
  11. 11.
    Kwon-Chung, K. J., Bennett, J. E. & Theodore, T. S., 1978. Cryptococcus bacillisporus sp. nov.: Serotype B-C of Cryptococcus neoformans. Int. J. Sys. Bacteriol. 28: 616–620.CrossRefGoogle Scholar
  12. 12.
    Muchmore, H. G., Scott, E. N., Felton, F. G., & Fromtling, R. A., 1980. Cryptococcus neoformans serotype groups encountered in Oklahoma. Am. J. Epidemiol. 112: 32–38.PubMedGoogle Scholar
  13. 13.
    Phaff, H. J. & Fell, J. W., 1970. Cryptococcus Kutzing emend. Phaff et Spencer. pp. 1088–1145. in: J. Lodder(ed.), The Yeasts, A Taxonomic Study. North Holland Publishing Co., Amsterdam.Google Scholar
  14. 14.
    Ruiz, A. & Bulmer, G. S., 1981. Particle size of airborne Cryptococcus neoformans in a tower. Appl. Environ. Microbiol. 41: 1225–1229.PubMedGoogle Scholar
  15. 15.
    Ruiz, A., Fromtling, R. A. & Bulmer, G. S., 1981. Distribution of Cryptococcus neoformans in a natural site. Infect. Immun. 31: 560–563.PubMedGoogle Scholar
  16. 16.
    Schmeding, K. A., Jong, S. C. & Hugh, R., 1981. Sexual compatibility between serotypes of Filobasidiella neoformans (Cryptococcus neoformans). Current Microbiol. 5: 133–138.CrossRefGoogle Scholar
  17. 17.
    Walter, J. E. & Coffee, E. G., 1968. Distribution and epidemiologic significance of the serotypes of Cryptococcus neoformans Am. J. Epidemiol. 87: 167–172.PubMedGoogle Scholar
  18. 18.
    Wickerham, L. J., 1951. Taxonomy of yeasts, p. 11. U.S.D.A. Tech. Bull. 1029. Government Printing Office, Washington, D.C.Google Scholar
  19. 19.
    Wilson, D. E., Bennett, J. E. and Bailey, J. W., 1968. Serologic grouping of Cryptococcus neoformans. Proc. Soc. Exp. Biol. Med. 127: 820–823.PubMedGoogle Scholar

Copyright information

© Dr W. Junk Publishers 1982

Authors and Affiliations

  • S. C. Jong
    • 1
  • G. S. Buhner
    • 2
  • A. Ruiz
    • 2
  1. 1.Mycology DepartmentAmerican Type Culture CollectionRockvilleUSA
  2. 2.Department of Microbiology and ImmunologyUniversity of Oklahoma Health Sciences CenterOklahoma CityUSA

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