, Volume 23, Issue 2, pp 121–123 | Cite as

Arthritis due to a penicillinase-producingNeisseria gonorrhoeae from Saudi Arabia

  • A. M. Kambal
Case Report


A case of arthritis due to a penicillinase-producingNeisseria gonorrhoeae in a 29-year-old lady is reported. The organism was isolated from the synovial fluid of the affected joint. Isolation of penicillinase-producingN. gonorrhoeae from such fluid has only rarely been reported. However, this is probably the first reported case from the Middle East and surrounding areas.


Public Health Arthritis Internal Medicine Infectious Disease General Practice 
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Arthritis durch pencillinasebildendeNeisseria gonorrhoeae. Fallbericht aus Saudi-Arabien


Eine 29jährige Frau erkrankte an einer Arthritis durch penicillinasebildendeNeisseria gonorrhoeae. Der Erreger wurde aus der Synovialflüssigkeit des betroffenen Gelenkes isoliert. Über die Isolation von penicillinasebildendenN. gonorrhoeae aus solchen Flüssigkeiten liegen nur wenig Berichte vor. Aus dem Mittleren Osten und umgebenden Regionen ist dies wahrscheinlich der erste Fallbericht.


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  1. 1.
    Goldenberg, D. I., Reed, J. I. Bacterial arthritis. N. Engl. J. Med. 312 (1985) 764–771.PubMedGoogle Scholar
  2. 2.
    McCord, W. C., Nies, K. M., Louie, J. S. Acute venereal arthritis. Arch. Intern. Med. 137 (1977) 858–862.PubMedGoogle Scholar
  3. 3.
    Brandt, K. D., Cathcart, E. S., Cohen, A. S. Gonococcal arthritis. Clinical features correlated with blood, synovial and genitourinary cultures. Arthritis Rheum. 17 (1974) 503–510.PubMedGoogle Scholar
  4. 4.
    Garcia-Kutzback, A., Dismuke, S. E., Masi, A. T. Gonococcal arthritis: clinical features and results of therapy. J. Rheumatol. 1 (1974) 210–221.PubMedGoogle Scholar
  5. 5.
    Handsfield, H. H., Wiesner, P. J., Holmes, K. K. Treatment of the gonococcal arthritis-dermatitis syndrome. Ann. Intern. Med. 84 (1976) 661–667.PubMedGoogle Scholar
  6. 6.
    Wiesner, P. J., Handsfield, H. H., Holmes, K. K. Low antibiotic resistance of gonococci causing disseminated infection. N Engl. J. Med. 288 (1973) 1221–1222.PubMedGoogle Scholar
  7. 7.
    Rinaldi, R. Z., Harrison, W. O., Fan, P. T. Penicillin-resistant gonococcal arthritis: A report of four cases. Ann. Intern. Med. 97 (1982) 43–45.PubMedGoogle Scholar
  8. 8.
    Leftik, M. I., Miller, J. W., Brown, J. D. Penicillin-resistant gonococcal polyarthritis. JAMA 239 (1978) 134.PubMedGoogle Scholar
  9. 9.
    Chowdhury, M. N. H., Pareek, S. S., Mahgoub, E. S. Penicillinase-producingNeisseria gonorrhoeae in Riyadh, Saudi Arabia. Br. J. Vener. Dis. 57 (1981) 256–258.PubMedGoogle Scholar
  10. 10.
    Stokes, E. J., Ridgway, G. L. Clinical Bacteriology. 6th ed. Edward Arnold, London 1987, pp. 204–221.Google Scholar
  11. 11.
    Barr, J., Danielsson, D. Septic gonococcal dermatitis. Br. Med. J. 1 (1971) 482–485.PubMedGoogle Scholar
  12. 12.
    Pritchard, C., Berney, S. N. Septic arthritis caused by penicillinase-producingNeisseria gonorrhoeae. J. Rheumatol. 15 (1988) 719–720.PubMedGoogle Scholar
  13. 13.
    Thompson, J., Dunbar, J. M., VanGent, A., Van Furth, R. Disseminated gonococcal infection due to a β-lactamase-producing strain ofNeisseria gonorrhoeae. Br. J. Vener. Dis. 57 (1981) 325–326.PubMedGoogle Scholar
  14. 14.
    Stewart, K., Carlson, M., Segal, A. M., White, C. S. Gonococcal arthritis caused by penicillinase-producing strains ofNeisseria gonorrhoeae. Arthritis Rheum. 44 (1985) 354–355.Google Scholar
  15. 15.
    Saraux, J. L., Vigneron, A. M., Berthelot, G., Dombret, M. C., Smiejan, J. M., Kahn, M. F. Disseminated gonococcal infection caused by penicillinase-producing organism with unusal joint involvement. J. Infect. Dis. 155 (1987) 154–155.PubMedGoogle Scholar
  16. 16.
    Strader, K. W., Wise, C. M., Wasilauskas, B. L., Salzer, W. L. Disseminated gonococcal infection caused by chromosomally mediated penicillin-resistant organisms. Ann. Intern. Med. 104 (1986) 365–366.PubMedGoogle Scholar
  17. 17.
    Ruutu, P., Rajala, R., Repo, H., Hirronven, P., Lahdevirta, J. Septicaemia caused by penicillinase-producing gonococcus. (Letter). JAMA 251 (1984) 1836.PubMedGoogle Scholar
  18. 18.
    Percival, A., Corkill, J. E., Arya, O. P., Rowlands, J., Alergant, C. D., Rees, E., Annels, E. H. Penicillinase-producing gonococci in Liverpool. Lancet ii (1976) 1379–1382.Google Scholar
  19. 19.
    Pizarro, S., Barile, L. Septic gonococcal arthritis. J. Rheumatol. 18 (1991) 941–942.PubMedGoogle Scholar
  20. 20.
    Hook, E. W. Septic gonococcal arthritis. Br. J. Rheumatol. 29 (1990) 283.PubMedGoogle Scholar
  21. 21.
    Bayer, A. S. Gonococcal arthritis syndromes, an update on diagnosis and management. Postgrad. Med. 67 (1980) 200–208.PubMedGoogle Scholar
  22. 22.
    Strongin, I. S., Kale, S. A., Raymond, M. K., Luskin, R. L., Weisberg, G. W., Jacobs, J. J. Unusual presentation of gonococcal arthritis in an HIV positive patient. Ann. Rheumatol. Dis. 50 (1991) 572–573.Google Scholar
  23. 23.
    Brighton, R. W., Wilding, K. Delayed diagnosis of gonococcal arthritis of the foot caused by β-lactamase-producingNeisseria gonorrhoeae. Med. J. Aust. 156 (1992) 368.Google Scholar
  24. 24.
    Bush, L. M., Boscia, J. A. Disseminated multiple antibiotic resistant gonococcal infection: needed changes in antimicrobial therapy. Ann. Intern. Med. 107 (1987) 692–693.PubMedGoogle Scholar

Copyright information

© MMV Medizin Verlag GmbH 1995

Authors and Affiliations

  • A. M. Kambal
    • 1
  1. 1.Dept. of Pathology and Microbiology (32)College of Medicine, King Saud UniversityRiyadhSaudi Arabia

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