Breast Cancer Research and Treatment

, Volume 23, Issue 3, pp 219–222 | Cite as

Prediction of hormone responsiveness by mammographic parenchymal pattern in advanced primary breast cancer

  • Niels Stig Møller Nielsen
  • Jørn Andersen
  • Hans Skovgaard Poulsen
  • Ole Mathiessen


Ninety-two women with advanced, unilateral breast cancer were classified according to the Wolfe and Nottingham classifications of mammographic parenchymal pattern (MPP). Both classifications of MPP were significantly correlated to the estrogen receptor (ER) status of the breast carcinoma, but could not be used for prediction of response to hormonal therapy. Age distribution was significantly different among Wolfe types as well as between ER groups, but a multiple regression analysis showed that both age and Wolfe pattern were significant and independent predictors of the ER status.

Key words

advanced breast cancer estrogen receptor hormone response mammographic parenchymal pattern 


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Copyright information

© Kluwer Academic Publishers 1992

Authors and Affiliations

  • Niels Stig Møller Nielsen
    • 1
  • Jørn Andersen
    • 2
  • Hans Skovgaard Poulsen
    • 3
  • Ole Mathiessen
    • 4
  1. 1.Dept. of Radiology R.The Aarhus University HospitalAarhus CDenmark
  2. 2.Dept. of OncologyRadiumstationenAarhus CDenmark
  3. 3.Danish Cancer Society, Department of Experimental Clinical OncologyRadiumstationen, Aarhus KommunehospitalAarhus CDenmark
  4. 4.Radiumstationen, Aalborg SygehusAalborgDenmark

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