Sympathetic skin response in Guillain-Barré syndrome
- 27 Downloads
Dysautonomia is a common feature of Guillain—Barré (GB) syndrome and is sometimes the cause of significant morbidity and death. Changes in sympathetic skin response (SSR) may be one of the accompaniments of dysautonomia. An attempt was made to correlate SSR changes with clinical and electrophysiologic features in a group of 24 patients with GB syndrome fulfilling NINDS (National Institute of Neurological Disorders and Stroke) criteria. A total of nine patients had absent SSR. Thirteen patients had clinical dysautonomia, of whom five had absent SSR. Five patients had features of predominant axonal damage and preserved SSR. A trend towards correlation of SSR abnormalities with common peroneal nerve conduction parameters (velocity and compound muscle action potential amplitude) was noted. We conclude that SSR abnormalities are common in GB syndrome and may be complementry to bed-side tests for autonomic dysfunction.
Keywordssympathetic skin response GB syndrome dysautonomia autonomic function tests
Unable to display preview. Download preview PDF.
- 1.Ropper AH, Wijdicks EFM, Traux BT. Electrophysiologic studies in Guillain-Barré syndrome. In:Guillain-Barré Syndrome. Contemporary Neurology series. Philadelphia: FA Davis, 1991; 161–174.Google Scholar
- 7.Taly AB, Muthane UB. Involvement of peripheral nervous system in Juvenile Parkinson's disease.Acta Neurol Scand 1992;85: 273–275.Google Scholar
- 9.Ropper AH, Wijdicks EFM, Traux BT. Clinical features of the typical syndrome. In:Guillain-Barré Syndrome. Contemporary Neurology series. Philadelphia: FA Davis, 1991; 73–105.Google Scholar
- 11.Low PA, McLeod JG. The autonomic neuropathies. In: Low PA, ed.Clinical Autonomic Disorders. London: Little Brown, 1993; 395–421.Google Scholar
- 13.Zochodne DW. Autonomic involvement in Guillain Barré Syndrome.Brain 1994;17: 1145–1155.Google Scholar