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BamHI polymorphism of locus D2S44 in a West German population as revealed by VNTR probe YNH24

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Summary

BamHI polymorphism at the VNTR locus D2S44 was investigated, concentrating on band frequencies, mutation rate and confirmation of Mendelian inheritance. In this series 39 restriction fragments showing frequencies less than 10% could clearly be distinguished. No mutations could be observed and the Mendelian character of inheritance is beyond reasonable doubt.

Zusammenfassung

Der locus-spezifische BamH1/YNH24-DNA-Polymorphismus wurde in einer westdeutschen Stichprobe (n = 122) untersucht mit dem Ziel, Daten über die Fragmenthäufigkeiten, Mutationsraten und Vererbungsweisen zu erhalten. 39 Restriktionsfragmente konnten zweifelsfrei voneinander unterschieden werden. Keines der Fragmente erreichte eine Häufigkeit von mehr als 10%. Die Restriktionsfragmente werden der autosomal kodominanten Vererbungsweise entsprechend vererbt. Hinweise auf eine Mutation liegen nicht vor.

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Authors and Affiliations

  1. Institut für Blutgruppenforschung, Abteilung Forensische Blutgruppenkunde und Molekulargenetik, Otto-Hahn-Strasse 39, W-4000, Düsseldorf 13, Germany

    L. Henke, S. Cleef, M. Zakrzewska & J. Henke

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  1. L. Henke
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  2. S. Cleef
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  3. M. Zakrzewska
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  4. J. Henke
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Henke, L., Cleef, S., Zakrzewska, M. et al. BamHI polymorphism of locus D2S44 in a West German population as revealed by VNTR probe YNH24. Int J Leg Med 104, 33–38 (1990). https://doi.org/10.1007/BF01816481

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  • DOI: https://doi.org/10.1007/BF01816481

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