Skip to main content
SpringerLink
Log in

Einbeziehung der Lewis-Blutgruppen in das Blutgruppengutachten

  • Published:
Blut Aims and scope Submit manuscript

Zusammenfassung

Lewis-Blutgruppen können heute dank potenter Antiseren zuverlässig und reproduzierbar bestimmt werden, so daß ihre Einbeziehung in das Blutgruppengutachten gerechtfertigt ist. Zu diesem Zweck wird die durch Wechselwirkungen der unabhängig voneinander vererbten ABH- und Lewis-Substanz-Sekretion resultierende und den Lewis-Gruppenbefund an den Blutkörperchen bestimmende genetische Hypothese dargelegt. Aus ihr werden die für das Blutgruppengutachten wichtigen Schlußfolgerungen (Ausschließung) und Parameter (Likelihood-Quotient Y/X nachEssen-Møller zur Vaterschaftsvermutung) abgeleitet und tabuliert.

Summary

Since it is now possible to determine the Lewis blood groups exactly because of the sufficient number of efficient anti-Lewis sera it is also justified to involve the Lewis blood groups in the paternity blood group opinion. Therefore that genetical hypothesis is presented explaining the Lewis blood groups by interaction of the independent heritable ABO and Lewis substance secretor status. From this hypothesis there are developped the process of paternity exclusion and the parameters of paternity presumption with the help of the likelihood ratio Y/X ofEssen-Møller in the Lewis blood group system and the obtained data are tabulated.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. Anderson, J., in: Modern views on the ABO blood groups and secretor status. (Ed. Jensen, K. G. and S.-A. Killmann). Series Haematol. Munksgaard, Copenhagen. Vol. 2, p. 34 (1969).

    Google Scholar 

  2. Ceppellini, R.: Proc. Vth Int. Congr. Blood Transf. Paris, p. 207 (1955a).

  3. Ceppellini, R.: Suppl. Ric. sci. Mem.25, 3 (1955b).

    Google Scholar 

  4. Ceppellini, R.: Ciba Found. Symp. Biochem. of Human Genetics, p. 242 (1959).

  5. Ceppellini, R., L. C. Dunn and F. Innella: Fol. hered. pathol.8, 261 (1959).

    Google Scholar 

  6. Essen-Moller, E.: Mitteil. Anthropos. Ges. (Wien)68, 9 (1938).

    Google Scholar 

  7. Grubb, R.: Nature (Lond.)162, 933 (1948).

    Google Scholar 

  8. Grubb, R.: Acta pathol. microbiol. scand.28, 61 (1951).

    PubMed  Google Scholar 

  9. Morgan, W. T. J.: Naturwissenschaften6, 181 (1959).

    Google Scholar 

  10. Race, R. R. and R. Sanger: Blood groups in man, p. 305, Blackwell, Oxford and Edinburgh (1968).

    Google Scholar 

  11. Sachs, V., J. Drews und B. Waldvogel: In Vorbereitung (1971).

  12. Sneath, J. S. and P. H. A. Sneath: Brit. med. Bull.15, 154 (1959).

    PubMed  Google Scholar 

  13. Watkins, W. M.: Proc. Xth Congr. Int. Soc. Blood Transf., p. 443, Stockholm (1965).

  14. Watkins, W. M. and W. T. J. Morgan: Vox Sang. (Basel)4, 97 (1959).

    Google Scholar 

Download references

Author information

Author notes

  1. V. Sachs

    Present address: Hygiene-Institut der Universität Kiel, Brunswicker Straße 2-6, D-23, Kiel

Authors and Affiliations

  1. Hygiene-Institut der Universität Kiel, Brunswicker Straße 2-6, D-23, Kiel

    J. Drews & B. Waldvogel

Authors
  1. V. Sachs
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. Drews
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. B. Waldvogel
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sachs, V., Drews, J. & Waldvogel, B. Einbeziehung der Lewis-Blutgruppen in das Blutgruppengutachten. Blut 23, 20–24 (1971). https://doi.org/10.1007/BF01815130

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01815130

Search

Navigation