Breast Cancer Research and Treatment

, Volume 12, Issue 3, pp 303–305 | Cite as

Complete remission after ovariectomy for advanced breast cancer correlated with estrogen receptor status and urinary androgen excretion

  • Saro Oriana
  • Giorgio Secreto
  • Giovanni Di Fronzo
  • Silvia Böhm
  • Andrea Torri
Brief communication

Summary

Our previous work showed urinary androgen excretion (A) as well as estrogen receptor (ER) to predict clinical response and survival after ovariectomy for advanced breast cancer. We here compare the complete responders with the partial responders to ovariectomy. The likelihood of CR (55% of responders) rather than PR was not strongly dependent on the location of metastases or on the ER/A status (though as noted previously there were no responses at all in the ER-/A- group), but CR did appear to increase survival.

Key words

estrogen receptors urinary androgens ovariectomy advanced breast cancer 

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References

  1. 1.
    Oriana S, Secreto G, Di Fronzo G, Torri A: Urinary androgens and tumor estrogen receptor as predictors of ovariectomy response and of survival in advanced breast cancer. Breast Cancer Res Treat 9: 201–205, 1987PubMedGoogle Scholar
  2. 2.
    Pedrazzini A, Cavalli F, Brunner KW, Goldhirsch A, Mermillod B: Complete remission following endocrine or combined cytotoxic and hormonal treatment in advanced breast cancer. A retrospective analysis. Oncology 44: 51–59, 1987PubMedGoogle Scholar

Copyright information

© Kluwer Academic Publishers 1988

Authors and Affiliations

  • Saro Oriana
    • 1
  • Giorgio Secreto
    • 1
  • Giovanni Di Fronzo
    • 1
  • Silvia Böhm
    • 1
  • Andrea Torri
    • 1
  1. 1.Istituto Nazionale per lo Studio e la Cura dei TumoriMilanItaly

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