Advertisement

The analysis of plasma and urinary organic acids during prolonged fasting differentiates between systemic carnitine deficiency and a defect of fatty acid oxidation

  • M. Duran
  • J. B. C. de Klerk
  • J. van Pelt
  • S. K. Wadman
  • H. R. Scholte
  • R. P. Beekman
  • F. G. I. Jennekens
Short Communication

Keywords

Public Health Internal Medicine Organic Acid Metabolic Disease Carnitine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Bartlett, K. and Gompertz, D. The specificity of glycine-N-acylase and acylglycine excretion in the organicacidaemias.Biochem. Med. 10 (1974) 15–23PubMedGoogle Scholar
  2. Gregersen, N., Lauritzen, R. and Rasmussen, K. Suberylglycine excretion in the urine from a patient with dicarboxylic aciduria.Clin. Chim. Acta 70 (1976) 417–425PubMedGoogle Scholar
  3. Kamerling, J. P., Brouwer, M., Ketting, D. and Wadman, S. K. Gas chromatography of urinaryN-phenylacetylglutamine.J. Chromatog. 164 (1979) 217–221Google Scholar
  4. Mortensen, P. B. and Gregersen, N. The biological origin of ketotic dicarboxylic aciduria.In vivo andin vitro investigations of theω-oxidation of C6–C16 monocarboxylic acids in unstarved, starved and diabetic rats.Biochim. Biophys. Acta 666 (1981) 394–404PubMedGoogle Scholar
  5. Pearson, D. J., Tubbs, P. K. and Chase, J. F. A. Carnitine and acylcarnitines.Methods Enzymol. 14 (1969) 1758–1771Google Scholar
  6. Saggerson, E. D. and Carpenter, C. A. Carnitine palmitoyltransferase and carnitine octanoyltransferase activities in liver, kidney cortex, adipocyte, lactating mammary gland, skeletal muscle and heart.FEBS Lett. 129 (1981) 229–232PubMedGoogle Scholar
  7. Staeffen, J., Rabinowitz, J. L., Aumonier, P., Ballen, P., Ferrer, J., Terme, R., Series, C. and Meyerson, R. M. Hyperoctanoatemia and the hepatic encephalopathy of cirrhosis.Nouv. Presse Méd. 8 (1979) 1663–1666Google Scholar

Copyright information

© SSIEM and MTP Press Limited 1983

Authors and Affiliations

  • M. Duran
    • 1
  • J. B. C. de Klerk
    • 1
  • J. van Pelt
    • 1
  • S. K. Wadman
    • 1
  • H. R. Scholte
    • 2
  • R. P. Beekman
    • 3
  • F. G. I. Jennekens
    • 4
  1. 1.University Children's Hospital ‘Het Wilhelmina Kinderziekenhuis’UtrechtThe Netherlands
  2. 2.Department of BiochemistryErasmus UniversityRotterdamThe Netherlands
  3. 3.Prinses Irene ZiekenhuisAlmeloThe Netherlands
  4. 4.Department of NeurologyUniversity HospitalUtrechtThe Netherlands

Personalised recommendations