Summary
We described two histochemical patterns of Ig G deposits in meningioma and discussed the pathogenesis of Ig G deposits. In meningioma with pseudopsammoma bodies, Ig G was secreted from tumour cells which differentiated to secretory epithelial cells, and was found to deposit in the pseudopsammoma bodies. However, in meningioma without pseudopsammoma bodies, Ig G was derived from plasma and became deposit around the blood vessels in the meningioma tissue.
Similar content being viewed by others
References
Baklien, K., Brandtzaek, P., Comparative mapping of the local distribution of immunoglobulin-containing cells in ulcerative colitis and Crohn's disease of the colon. Clin. exp. Immunol.22 (1975), 197–209.
Berard, M., Tripier, M. F., Choux, R., Chrestian, M. A., Hassoun, J., Toga, M., Erude ultrastructure des corps hyalins dún Méningiome pseudépithélial. Acta Neuropath.42 (1975), 614–617.
Brandtzaeg, P., Transport models for secretory Ig A and secretory Ig M. Clin. exp. Immunol.44 (1981), 221–232.
Budka, H., Hyaline inclusions (pseudopsammoma bodies) in meningiomas: Immunocytochemical demonstration of epithellike secretion of secretory component and immunoglobulin A and M. Acta Neuropathol.56 (1982), 294–298.
Cushing, H., Eisenhardt, L., In: Meningiomas. Their Classification, Regional Behavior, Life History and Surgical End Results. Part I, pp. 175. New York: Hafner. 1962.
Font, R. L., Croxaytto, L. O., Intracellular inclusions in meningotheliomatous meningioma. A histochemical and ultrastructural study. J. Neuropathol.39 (1980), 575–583.
Horten, B. C., Urich, H., Stefoski, D., Meningiomas with conspicuous plasma cell-lymphocytic components. A report of five cases. Cancer43 (1979), 258–264.
Kawakami, Y., Immunofluorescent study of immunoglobulins and complement components in human brain tumors. Acta Med. Okayama35 (1981), 103–116.
Kepes, J., Observations on the formation of psammoma bodies and pseudopsammoma bodies in meningiomas. J. Neuropathol.20 (1961), 255–262.
Kepes, J., The fine structure of hyaline inclusion (pseudopsammoma bodies) in meningioma. J. Neuropathol. exp. Neurol.34 (1975), 282–289.
Kock, K. F., Teglbjaerg, P. S., Meningiomas with a non-meningotheliomatous component. A new type of tumor. Acta Neuropathol.55 (1981), 199–203.
Kuratsu, J., Matsukado, Y., Sonoda, H., Pseudopsammoma bodies in meningotheliomatous meningioma. A histochemical and ultrastructural study. Acta Neurochir. (Wien)68 (1983), 55–62.
Lambert, P. W., Oldstone, M. B. A., Host immunoglobulin G and complement deposits in the choroid plexus during spontaneous immune complex disease. Science180 (1983), 408–410.
Mottet, S., Martin-Achard, A., de Tribolet, N., Diserens, A. C., Evaluation of the humoral response of meningioma patients to possible common tumour-associated antigens. Acta Neurochir. (Wien)52 (1980), 19–25.
Nyström, S. H., A study of supratentorial meningiomas with special reference to gross and fine structure. Acta Pathol. (Microbiol. Scand.) (Suppl.)176 (1965), 1–90.
Pees, H. W., Cytotoxic immune response of meningioma patients towards allogeneic and autologous tumor cells before and after surgery. Acta Neurochir. (Wien)50 (1979), 217–227.
Stam, F. C., van Alphen, A. M., Boorsma, D. M., Meningioma with conspicuous plasma cell components. A histopathological and immunohistochemical study. Acta Neuropathol.49 (1980), 241–243.
Syré, G., Sehn, M., Intracellular storage of Ig A and secretory component in carcinomas of the female breast. Virchows Arch.393 (1981), 315–320.
Tabuchi, K., Kawakami, Y., Nishimoto, A., Immunohistochemical demonstration of Ig G in meningioma. Acta Neurochir. (Wien)55 (1981), 201–211.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kuratsu, J., Matsukado, Y., Hattori, R. et al. Immunopathological significance of Ig G in meningioma in relation to the pseudopsammoma bodies. Acta neurochir 78, 38–42 (1985). https://doi.org/10.1007/BF01809239
Issue Date:
DOI: https://doi.org/10.1007/BF01809239