Abstract
The recent suggestion (Root-Bernstein, 1982) that the homochirality of amino acids and sugars in the current biosphere may have originated as a result of novel organic ‘selector molecules’ is examined critically. It is concluded that such selector molecules are non-existent as described, and that their postulation is based on chemical and stereochemical misconceptions.
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Blumenthal, S. J.: 1984,BioEssays 1, 258; 1985,J. Theor. Biol. 114, 665.
Bonner, W. A.: 1988, ‘Origins of Chiral Homogeneity in Nature’ in Eliel, E. L. and Wilen, S. H. (eds.),Topics in Stereochemistry, Vol. 18, John Wiley & Sons, New York, pp. 1–96.
Davis, F. A. and Jenkins, Jr., R. H.: 1984, ‘Synthesis and Utilization of Compounds with Chiral Nitrogen Centers’, in Morrison J. D. and Scott, J. W. (eds.),Asymmetric Synthesis, Vol. 4, Academic Press, Inc., New York, p. 313.
De Min, M., Levy, G., and Micheau, J. C.: 1988,J. Chim. Phys. 85(5), 603.
Kessler, H.: 1970,Angew. Chem. Int. Ed. Engl. 9, 219.
Lehn, J. M.: 1970,Top. Curr. Chem. 15, 311, esp. 343.
Nygaard, L., Nielson, J. T., Kirchheiner, J., Maltesen, G., Rastrup-Andersen, J., and Sorensen, G. O.: 1969,J. Mol. Struct. 3, 491.
Pleasant, L. G. and Ponnamperuma, C.: 1984,Origins of Life 15, 55.
Portelli, C.: 1981,J. Theor. Biol. 93, 93; 1987,Specul. Sci. Techn. 10, 89.
Prelog, V. and Wieland, P.: 1944,Helv. Chim. Acta 27, 1127.
Root-Bernstein, R. S., 1982,J. Theor. Biol. 99, 101.
Sygula, A. and Buda, A.: 1985,J. Mol. Struct. (Theochem.) 121, 133.
Thomas, D. E.: 1980,Sci. Am. 243 (Dec.), 206.
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Bonner, W.A. Selective chirality — A closer examination. Origins Life Evol Biosphere 20, 411–417 (1990). https://doi.org/10.1007/BF01808135
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DOI: https://doi.org/10.1007/BF01808135