Oestrogen and progesterone receptor content and the distribution of histological grade in breast cancer
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Histological grading of 160 primary infiltrating breast carcinomas showed that both oestrogen and progesterone receptor status are strongly related to grade, tumours that are receptor positive tending to be of lower grade than the receptor negative.
The nuclear factors used in grading were those that determined this association. In addition the absence/presence of both receptors was reflected in the grade present, beyond the correlation expected on the basis of either receptor alone.
Keywordsbreast cancer histological grade steroid receptors
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- 1.McGuire WL, Pearson OH, Segaloff A: Predicting hormone responsiveness in human breast cancer.In WL McGuire, PP Carbone, and EP Vollmer (eds): Estrogen Receptors in Human Breast Cancer. Raven Press, New York, 1975, pp 17–30Google Scholar
- 6.Würz H, Citoler P, Schülz KD, Roos B, Kaiser R: Correlation of steroid hormone receptor levels with histological grading in human breast cancer. Klin Wschr 58: 643, 1981Google Scholar
- 8.Scharff RW, Torloni H: Histological typing of breast tumours. Wld Hlth Org, Geneva, 1968, No. 2, pp 17–18Google Scholar
- 11.Schi∅dt T: Breast Carcinoma. A histological and prognostic study of 650 followed up cases. Munksgaard, Copenhagen, 1966Google Scholar
- 12.Bunting JS, Kremer JK: Breast cancer and histological grade. Lancet ii: 364, 1981Google Scholar
- 14.Thoresen S: Histological grade and clinical stage at presentation in breast carcinoma. Br J Cancer (in press)Google Scholar