Breast Cancer Research and Treatment

, Volume 3, Issue 2, pp 201–207 | Cite as

Relationship between mammographic pattern and estrogen receptor content in breast cancer

  • Anette Broberg
  • Ulla Glas
  • Sven A. Gustafsson
  • Lars Hellström
  • Anders Somell


The mammographic pattern and its relationship to the estrogen receptor (ER) content was studied in 184 breast cancers. The tumors were divided into five radiographic subgroups: mass with spicules (A), diffuse (B), clusters of calcifications without a mass (C), circumscribed (D), and not visible at mammography (E). The ER content of tumors belonging to group A was higher than that of the other subgroups in both pre- and postmenopausal women. 121 tumors belonged to group A, of which 80% were ductal cancers. The tumors in groups B and C had very low ER values and those of groups D and E had intermediate values.

The likelihood of finding a high estrogen receptor content of a tumor is thus greater when the tumor radiographically is seen as a mass with spicules than when seen as an increased attenuation or as only clusters of calcifications. It is suggested that patients with tumors belonging to group A should have a more favorable prognosis than patients with tumors belonging to groups B and C.


breast cancer estrogen receptor mammographic pattern 


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Copyright information

© Martinus Nijhoff Publishers 1983

Authors and Affiliations

  • Anette Broberg
    • 1
  • Ulla Glas
    • 1
  • Sven A. Gustafsson
    • 2
  • Lars Hellström
    • 1
  • Anders Somell
    • 1
  1. 1.Departments of Surgery, Radiology, and OncologyKarolinska Institute at SödersjukhusetStockholmSweden
  2. 2.Department of Clinical ChemistryHuddinge HospitalHuddingeSweden

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