References
Blass, J. P. In Burman, D., Holton, J. B. and Pennock, C. A. (eds.)Inherited Disorders of Carbohydrate Metabolism, MTP Press, Lancaster, 1980, pp. 239–268
Blass, J. P., Cederbaum, S. D. and Kark, R. A. P. Rapid diagnosis of pyruvate and ketoglutarate dehydrogenase deficiencies in platelet-enriched preparations from blood.Clin. Chim. Acta 75 (1977) 21–30
DeVivo, D. C., Haymond, M. W., Obert, K. A., Nelson, J. S. and Pagliara, A. S. Defective activation of the pyruvate dehydrogenase complex in subacute necrotizing encephalomyelopathy (Leigh's disease).Ann. Neurol. 6 (1979) 483–494
Evans, O. B. Human muscle pyruvate dehydrogenase activity.Neurology (NY) 33 (1983) 1463–1471
Harris, R. A., Paxton, R. and Parker, R. A. Activation of the branched-chain α-ketoacid dehydrogenase complex by a broad specificity protein phosphatase.Biochem. Biophys. Res. Commun. 107 (1982) 1497–1503
Reed, L. J. Multienzyme complexes.Accts. Chem. Res. 7 (1974) 40–46
Sheu, K. F. R., Hu, C. W. C. and Utter, M. F. Pyruvate dehydrogenase complex activity in normal and deficient fibroblasts.J. Clin. Invest. 67 (1981) 1463–1471
Toshima, K., Kuroda, Y., Hashimoto, T., Ito, M., Watanabe, T., Miyao, M. and Ii, K. Enzymologic studies and therapy of Leigh's disease associated with pyruvate decarboxylase deficiency.Pediatr. Res. 16 (1982) 430–435
Wieland, O. H., Siess, E., Schultze-Wethmar, F. H., von Funcke, H. G. and Winton, B. Active and inactive forms of pyruvate dehydrogenase in rat heart and kidney: effect of diabetes, fasting and refeeding on pyruvate dehydrogenase interconversion.Arch. Biochem. Biophys. 143 (1971) 593–601
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Toshima, K., Kuroda, Y., Takeda, E. et al. In vitro activation of the pyruvate dehydrogenase complex in human muscle by a broad specificity protein phosphatase. J Inherit Metab Dis 7, 143–144 (1984). https://doi.org/10.1007/BF01801778
Issue Date:
DOI: https://doi.org/10.1007/BF01801778