Keratan sulphate excretion in a patient with Kniest dysplasia
The clinical and radiological features of a patient with Kniest dysplasia, a form of metatropic dwarfism, are described. The patient excreted glycosaminoglycans (mucopolysaccharides) in normal amounts during infancy but subsequently showed abnormal keratan sulphate excretion. The significance of these findings and the possibility that Kniest dysplasia represents another mucopolysaccharidosis are discussed.
KeywordsPublic Health Sulphate Internal Medicine Metabolic Disease Normal Amount
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