Journal of Inherited Metabolic Disease

, Volume 5, Issue 2, pp 111–113 | Cite as

Normal hydroxylation of proline in collagen synthesized by skin fibroblasts from a patient with prolidase deficiency

  • P. M. Royce
  • D. M. Danks


The extent of hydroxylation of proline in collagen synthesized and secreted into the culture medium by skin fibroblasts derived from a patient with prolidase deficiency has been examined and found to be normal. It would seem likely that to a considerable extent the urinary proline-containing dipeptides apparent in this condition are derived from sources other than collagen.


Public Health Collagen Internal Medicine Proline Metabolic Disease 
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Copyright information

© MTP Press Limited 1982

Authors and Affiliations

  • P. M. Royce
    • 1
  • D. M. Danks
    • 1
    • 2
  1. 1.Genetics Research UnitRoyal Children's Hospital Research FoundationParkvilleAustrialia
  2. 2.Department of PaediatricsUniversity of MelbourneParkvilleAustralia

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