Journal of Inherited Metabolic Disease

, Volume 14, Issue 5, pp 698–706 | Cite as

Fifteen years' experience with 212 hyperammonaemic cases at a Metabolic Unit

  • A. Tokatli
  • T. Coşkun
  • İ Özalp


Two hundred and twelve cases with hyperammonaemia, diagnosed at the Metabolic Unit of Hacettepe Children's Hospital over the past 15 years, were evaluated both clinically and biochemically.


Sodium Valproate Perinatal Asphyxia Ductus Venosus Organic Aciduria Metabolic Unit 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Bachmann, C. Urea cycle disorders. In Fernandes, J., Saudubray, J.-M., Tada, K. (eds.)Inborn Metabolic Diseases, Springer-Verlag, Berlin, 1990, pp. 211–229Google Scholar
  2. Batshaw, M. L. Hyperammonaemia.Curr. Prob. Pediatr. 14 (1984) 1–69CrossRefGoogle Scholar
  3. Batshaw, M. L. and Brusilow, S. W. Valproate-induced hyperammonaemia.Ann. Neurol. 11 (1982) 319–321PubMedCrossRefGoogle Scholar
  4. Brusilow, P. W., Batshaw, M. L. and Waber, L. Neonatal hyperammonaemic coma.Adv. Pediatr. 29 (1982) 69–103PubMedGoogle Scholar
  5. Koçak, N. and Özsoylu, S. Familial cirrhosis.Am. J. Dis. Child. 133 (1979) 1160–1162PubMedGoogle Scholar
  6. Müller-Beissenhirtz, W. Eine einfache Methode zur Bestimmung des Blutammoniaks.Fresenius Zeitschriks für analytische Chemie, Labor und Betriebsvereahren 212 (1965) 145–155CrossRefGoogle Scholar
  7. Rowe, P. C., Valle, D. and Brusilow, S. W. Inborn errors of metabolism in children referred with Reye's syndrome.J. Am. Med. Assoc. 260 (1988) 3167–3170CrossRefGoogle Scholar
  8. Shih, V. E. Amino acids. In Shih, V. E. (ed.)Laboratory Techniques for the Detection of Hereditary Metabolic Disorders, CRC Press, Ohio, 1973, p. 11Google Scholar
  9. Tunçbilek, E. and Ulusoy, M. Consanguinity in Turkey in 1988.J. Population Stud. 11 (1989) 35–46Google Scholar
  10. Waldman, R. J., Hall, W. N., McGee, al. Aspirin as a risk factor in Reye's syndrome.J. Am. Med. Assoc. 247 (1982) 3089–3094CrossRefGoogle Scholar

Copyright information

© SSIEM and Kluwer Academic Publishers 1991

Authors and Affiliations

  • A. Tokatli
    • 1
  • T. Coşkun
    • 1
  • İ Özalp
    • 1
  1. 1.Department of Metabolism and Nutrition, Institute of Child HealthHacettepe UniversityAnkaraTurkey

Personalised recommendations